OriGene

CBR3 Monoclonal Antibody (OTI1G6), TrueMAB™

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CBR3 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical staining of paraffin-embedded human prostate tissue within the normal limits using anti-CBR3 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA503225)

CBR3 Antibody in Western Blot (WB) — HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CBR3 (RC201073, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CBR3. Positive lysates LY420049 (100 µg) and LC420049 (20 µg) can be purchased separately from OriGene.

Product Details

TA503225

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:150	-

Product Specifications
Species Reactivity	Dog, Human, Mouse, Rat
Host/Isotype	Mouse / IgG1
Class	Monoclonal
Type	Antibody
Clone	OTI1G6
Immunogen	Full length human recombinant protein of human CBR3 produced in HEK293T cell. View antigen
Conjugate	Unconjugated
Form	liquid
Concentration	0.43 mg/mL
Purification	Affinity chromatography
Storage buffer	PBS with 1% BSA, 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles

Target Information

Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: carbonyl reductase (NADPH) 3; Carbonyl reductase [NADPH] 3; epididymis secretory protein Li 25; NADPH-dependent carbonyl reductase 3; Short chain dehydrogenase/reductase family 21C member 2; short chain dehydrogenase/reductase family 21C, member 2

Gene Aliases: 1110001J05Rik; C81353; CBR3; hCBR3; HEL-S-25; SDR21C2

UniProt ID: (Human) O75828, (Mouse) Q8K354

Entrez Gene ID: (Dog) 487748, (Human) 874, (Mouse) 109857, (Rat) 304078

Molecular Function: reductase