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MA5-17273 targets CBS in WB applications and shows reactivity with Human, Mouse, and Rat samples.
The MA5-17273 immunogen is recombinant protein fragment contains a sequence corresponding to a region within amino acids 39 and 251 of CBS.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Beta-thionase; Cystathionine beta-synthase; Cystathionine beta-synthase-like protein; cystathionine-beta-synthase; Hemoprotein H-450; HIP4; methylcysteine synthase; Serine sulfhydrase
Gene Aliases: AI047524; AI303044; CBS; CBSL; HIP4
UniProt ID: (Human) P0DN79, (Rat) P32232, (Mouse) Q91WT9
Entrez Gene ID: (Human) 875, (Rat) 24250, (Mouse) 12411
Molecular Function:
deaminase
dehydratase
epimerase/racemase
hydrolase
isomerase
lyase
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