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This antibody recognizes CBX2 (Chromobox protein homolog 2). It binds to a folded domain, amino acids 2-70. CBX2 is a component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.
MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cell division cycle associated 6; chromobox homolog 2 (Pc class homolog, Drosophila); Chromobox protein homolog 2; modifier 3; Pc class homolog
Gene Aliases: CBX2; CDCA6; M33; SRXY5
UniProt ID: (Human) Q14781
Entrez Gene ID: (Human) 84733
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