|Tested species reactivity||Dog, Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide region of human HTATIP2.|
|Storage buffer||PBS with 2% sucrose|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||4-8 µg/ml|
|Western Blot (WB)||10 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-24473 detects CC3 (HTATIP2) in Human samples.
PA1-24473 has been successfully used in Western Blot and immunohistochemistry (paraffin) procedures. While diluting for Western blot, use a 5% skim milk/PBS buffer solution.
PA1-24473 immunogen corresponds to Polyclonal antibody from rabbits immunized with a synthetic peptide region of human HTATIP2.
CC3 (HTATIP2) is a member of the short-chain dehydrogenases/reductases (SDR) family. It is a novel serine/threonine kinase that phosphorylates the C-terminal domain (CTD) of the largest RNA polymerase II subunit and induces the expression of apoptosis related genes Bad and Siva, as well as metastasis suppressor NM23-H2. It also interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates ERalpha-mediated c-myc transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.