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FIGURE: 1 / 2
CCDC94 Antibody (68324-1-IG) in WB
Various lysates were subjected to SDS PAGE followed by western blot with 68324-1-Ig (CCDC94 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control.
Product Details
68324-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1D1G9
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MSERKVLNKY YPPDFDPSKI PKLKLPKDRQ YVVRLMAPFN MRCKTCGEYI YKGKKFNARK ETVQNEVYLG LPIFRFYIKC TRCLAEITFK TDPENTDYTM EHGATRNFQA EKLLEEEEKR VQKEREDEEL NNPMKVLENR TKDSKLEMEV LENLQELKDL NQRQAHVDFE AMLRQHRLSE EERRRQQQEE DEQETAALLE EARKRRLLED SDSEDEAAPS PLQPALRPNP TAILDEAPKP KRKVEVWEQS VGSLGSRPPL SRLVVVKKAK ADPDCSNGQP QAAPTPGAPQ NRKEANPTPL TPGASSLSQL GAYLDSDDSN GSN
Target Information
Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA (PubMed:29301961). Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex (PubMed:22952453). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coiled-coil domain-containing protein 94; Splicing factor YJU2
Gene Aliases: 2900016D05Rik; AI413813; CCDC94; YJU2
UniProt ID: (Human) Q9BW85, (Mouse) Q9D6J3
Entrez Gene ID: (Human) 55702, (Rat) 501285, (Mouse) 72886
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