This antibody is predicted to react with Monkey, Dog, Cat and Horse
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 6Ckine; beta chemokine exodus-2; Beta-chemokine exodus-2; C-C motif chemokine 21; C-C motif chemokine 21a; C-C motif chemokine 21b; C-C motif chemokine 21c; C-C Motif Chemokine Ligand 21; CC chemokine 6Ckine-ser; Ccl21-leu; CCL21-Ser; chemokine (C-C motif) ligand 21; Efficient Chemoattractant for Lymphocytes; exodus-2; secondary lymphoid organ chemokine; secondary lymphoid tissue chemokine; Secondary lymphoid-tissue chemokine; SLC; small inducible cytokine A21; small inducible cytokine A21a; small inducible cytokine A21c; small inducible cytokine subfamily A (Cys-Cys), member 21; Small-inducible cytokine A21; Small-inducible cytokine A21a; Small-inducible cytokine A21b; Small-inducible cytokine A21c; TCA4; Thymus-derived chemotactic agent 4
Gene Aliases: 6CKBAC1; 6CKBAC2; 6Ckine; AI159701; ALP; AW987545; CCL21; Ccl21a; Ccl21b; Ccl21c; CKb9; ECL; exodus-2; plt; SCYA21; SCYA21a; Scya21b; Scya21c; SLC; TCA4; UNQ784/PRO1600