Invitrogen

CCL3 (MIP-1 alpha) Polyclonal Antibody

View all (27) CCL3 (MIP-1 alpha) antibodies

Questions & Answers

Questions & Answers

Product Image Gallery

CCL3 (MIP-1 alpha) Antibody in Immunocytochemistry (ICC/IF) — Immunocytochemistry-Immunofluorescence analysis of PANC-1 cells using CCL3 (MIP-1 alpha) Polyclonal Antibody (Product # PA5-120000).

CCL3 (MIP-1 alpha) Antibody in Immunocytochemistry (ICC/IF) — Immunocytochemistry-Immunofluorescence analysis of A549 cells using CCL3 (MIP-1 alpha) Polyclonal Antibody (Product # PA5-120000).

CCL3 (MIP-1 alpha) Antibody in Immunocytochemistry (ICC/IF) — Immunocytochemistry-Immunofluorescence analysis of Hela cells using CCL3 (MIP-1 alpha) Polyclonal Antibody (Product # PA5-120000).

CCL3 (MIP-1 alpha) Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis of paraffin- embedded mouse pancreas tissue using CCL3 (MIP-1 alpha) Polyclonal Antibody (Product # PA5-120000).

CCL3 (MIP-1 alpha) Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis of paraffin- embedded mouse spleen tissue using CCL3 (MIP-1 alpha) Polyclonal Antibody (Product # PA5-120000).

CCL3 (MIP-1 alpha) Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry (Paraffin) analysis of paraffin- embedded mouse lung tissue using CCL3 (MIP-1 alpha) Polyclonal Antibody (Product # PA5-120000).

CCL3 (MIP-1 alpha) Antibody in Flow Cytometry (Flow) — Flow Cytometry analysis of CCL3 (MIP-1 alpha) in HeLa cells using CCL3 (MIP-1 alpha) Polyclonal Antibody (Product # PA5-120000) at 1:100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.

Product Details

PA5-120000

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500	-
Immunohistochemistry (Paraffin) (IHC (P))	1:50-1:200	-
Immunocytochemistry (ICC/IF)	1:50-1:200	-
Flow Cytometry (Flow)	1:50-1:100	-

Product Specifications
Species Reactivity	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Synthetic peptide within N-terminal mouse CCL3
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Affinity chromatography
Storage buffer	PBS, pH 7.4, with 40% glycerol, 0.2% BSA
Contains	0.05% sodium azide
Storage conditions	Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Product Specific Information

Positive Control: Hela, PANC-1, A549, mouse pancreas tissue, mouse lung tissue, mouse spleen tissue

Subcellular Location: Secreted

Target Information

Macrophage inflammatory protein-1a (MIP-1a) is an 8kDa member of the C-C chemokine subfamily. C-C chemokines are chemoattractants and activators for monocytes and T cells. MIP-1a has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1b and RANTES.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

References (0)

Have you cited this product in a publication?

Let us know so we can reference it here.

Cite this product

Bioinformatics

Protein Aliases: C-C motif chemokine 3; chemokine (C-C motif) ligand 3; G0/G1 switch regulatory protein 19-1; H-MIP-1-alpha; Heparin-binding chemotaxis protein; L2G25B; LD78-alpha; LD78-alpha(4-69); Macrophage inflammatory protein 1-alpha; macrophage inflammatory protein-1alpha; MIP-1 alpha; MIP-1-alpha; MIP-1-alpha(4-69); MIP1 (a); mip1 alpha; PAT 464.1; RP23-320E6.7; SIS-alpha; SIS-beta; small inducible cytokine A3; small inducible cytokine A3 (homologous to mouse Mip-1a); Small-inducible cytokine A3; Tonsillar lymphocyte LD78 alpha protein; TY-5

Gene Aliases: AI323804; CCL3; G0S19-1; LD78ALPHA; MIP-1-alpha; MIP-1alpha; MIP1-(a); MIP1-alpha; MIP1A; SCYA3

UniProt ID: (Human) P10147, (Mouse) P10855

Entrez Gene ID: (Human) 6348, (Mouse) 20302

Molecular Function: cytokine intercellular signal molecule

MAPK cascade osteoblast differentiation cell activation monocyte chemotaxis calcium ion transport cellular calcium ion homeostasis exocytosis chemotaxis inflammatory response cytoskeleton organization G-protein coupled receptor signaling pathway cell-cell signaling behavior regulation of cell shape response to toxic substance positive regulation of gene expression negative regulation of gene expression T cell chemotaxis release of sequestered calcium ion into cytosol by sarcoplasmic reticulum calcium-mediated signaling signaling positive regulation of cell migration negative regulation of bone mineralization neutrophil chemotaxis lipopolysaccharide-mediated signaling pathway positive regulation of tumor necrosis factor production eosinophil degranulation protein kinase B signaling positive regulation of neuron apoptotic process positive regulation of GTPase activity astrocyte cell migration negative regulation by host of viral transcription negative regulation of osteoclast differentiation eosinophil chemotaxis macrophage chemotaxis lymphocyte chemotaxis positive regulation of interleukin-1 beta secretion positive regulation of inflammatory response positive regulation of calcium-mediated signaling positive chemotaxis positive regulation of protein kinase B signaling positive regulation of calcium ion transport regulation of sensory perception of pain chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade response to cholesterol cellular response to interferon-gamma cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to organic cyclic compound granulocyte chemotaxis positive regulation of calcium ion import positive regulation of natural killer cell chemotaxis immune response positive regulation of cytosolic calcium ion concentration leukocyte chemotaxis positive regulation of osteoclast differentiation positive regulation of transcription from RNA polymerase II promoter cell chemotaxis

Process(es)

protein kinase activity calcium-dependent protein kinase C activity protein binding chemokine activity phospholipase activator activity kinase activity CCR1 chemokine receptor binding CCR5 chemokine receptor binding chemoattractant activity identical protein binding cytokine activity