This antibody detects recombinant mouse (rm)CCL5 direct ELISAs. In sandwich ELISAs, approximately 5% cross-reactivity with rhCCL5 and less than 0.2% cross-reactivity with rhTECK and rhVIC was observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV). It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-C motif chemokine 5; MGC17164; MuRantes; OTTHUMP00000197106; SIS ¿¿; SIS-delta; SIS¿¿; small inducible cytokine A5; Small-inducible cytokine A5; T-cell-specific protein RANTES
Gene Aliases: Ccl5; MuRantes; RANTES; Scya5; SISd; TCP228
UniProt ID: (Mouse) P30882
Entrez Gene ID: (Mouse) 20304