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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Recombinant fragment corresponding to residues 211-377 of human CCN1.|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-25681 detects CCN1 from human, mouse, and rat samples.
PA1-25681 has been successfully used in Western blot procedures.
The PA1-25681 immunogen is a recombinant fragment corresponding to residues 211-377 of human CCN1.
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
3CH61; CCN family member 1; CCN1; CCNA; cysteine rich protein 61; cysteine-rich angiogenic inducer 61; cysteine-rich heparin-binding protein 61; cysteine-rich, angiogenic inducer, 61; cysteine-rich, anigogenic inducer, 61; IBP-10; IGF-binding protein 10; IGFBP-10; insulin-like growth factor binding protein 10; insulin-like growth factor-binding protein 10; intermediate early; protein CYR61
AI325051; CCN1; CYR61; GIG1; IGFBP10