|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rat / IgG2a|
|Immunogen||Human CCR5 transfected into CHO cells.|
|Storage buffer||PBS with 1% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Neat-1:10 (10 µl for 10^6 cells in 100 µl)|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-20282 detects CCR5 in human samples.
MA1-20282 has been successfully used in FACS procedures.
The MA1-20282 immunogen is human CCR5 transfected into CHO cells.
Receptors for the CC chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5 and the Duffy blood group antigen. The CC receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. The HIV receptor is composed of two molecules, the CD4 binding receptor and a co receptor. The chemokine receptor CCR5 is one of the co receptors used by primary isolates of HIV1. Extracellular domains of CCR5 are important for HIV entry into the target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.