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|Tested species reactivity||Human, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide demonstrating a high affinity towards the monoclonal CCR5 2D7 (2D7-2SK) residues: EWQKEGLVTLWLGGGGSC|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||1 µg/ml|
|Flow Cytometry (Flow)||25 µg/ml|
|Functional Assay (FN)||Assay-Dependent|
|In vitro Assay (IV)||Assay-Dependent|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is useful for inhibition of CCR5 tropic HIV envelope mediated fusion, syncytia formation, and infection in various in vitro assays.
CCR5 is a major coreceptor for human HIV infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
C-C chemokine receptor type 5; C-C CKR-5; C-C motif chemokine receptor 5 A159A; CC-CKR-5; CD195 antigen; chemokine receptor CCR5; chemr13; CMKBR5; HIV-1 fusion coreceptor
CC-CKR-5; CCCKR5; CCR-5; CD195; CKR-5; CKR5; CMKBR5; IDDM22