|Flow Cytometry (Flow)||1-3 µl for 10^6 cells in 100 µl|
|Immunohistochemistry (Paraffin) (IHC (P))||1:250|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide corresponding to residues V(12) T D Y Y Y P D I F S S P C D A E L I Q T N G K L C(36) of human CCR8.|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M potassium phosphate, pH 7.2, with 0.14M NaCl, 1mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-21621 detects CCR8 in human samples.
PA1-21621 has been successfully used in ELISA, FACS, immunocytochemistry, immunohistochemistry (paraffin) and Western blot procedures.
The PA1-21621 immunogen is a synthetic peptide corresponding to residues V(12) T D Y Y Y P D I F S S P C D A E L I Q T N G K L C(36) of human CCR8.
Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-C chemokine receptor type 8; C-C CKR-8; CC chemokine receptor 8; CC chemokine receptor CHEMR1; CC-chemokine receptor chemr1; CDw198; chemokine (C-C motif) receptor 8; chemokine (C-C) receptor 8; chemokine (C-C) receptor-like 2; Chemokine receptor-like 1; CKR-L1; CKRL1; CMKBR8; CMKBRL2; CY6; GPR-CY6; GPRCY6; MGC129966; MGC129973; TER1
Gene Aliases: CC-CKR-8; CCR-8; CCR8; CDw198; CKRL1; CMKBR8; CMKBRL2; CY6; GPRCY6; TER1
UniProt ID: (Human) P51685
Entrez Gene ID: (Human) 1237
Molecular Function: G-protein coupled receptor cell adhesion molecule cytokine receptor defense/immunity protein hydrolase immunoglobulin receptor superfamily immunoglobulin superfamily cell adhesion molecule phosphatase protein phosphatase receptor
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