|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||PBS with BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.
CD10 (neutral endopeptidase - NEP, common acute lymphocytic leukemia antigen - CALLA, membrane metallo-endopeptidase - MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.
Analyte Specific Reagent
B-cell reconstitution after lentiviral vector-mediated gene therapy in patients with Wiskott-Aldrich syndrome.
CD1001 was used in flow cytometry to discuss the use of stem cells to treat Wiskott-Aldrich syndrome.
|Castiello MC,Scaramuzza S,Pala F,Ferrua F,Uva P,Brigida I,Sereni L,van der Burg M,Ottaviano G,Albert MH,Grazia Roncarolo M,Naldini L,Aiuti A,Villa A,Bosticardo M||The Journal of allergy and clinical immunology (136:692)||2015|
|Not Applicable||Not Cited||
Graft source determines human hematopoietic progenitor distribution pattern within the CD34(+) compartment.
CD1001 was used in flow cytometry to characterize the cells in the CD34(+) compartment of grafts
|Arber C,Halter J,Stern M,Rovó A,Gratwohl A,Tichelli A||Bone marrow transplantation (46:650)||2011|