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|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Pre-B cell line NALM-6.|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 ug/ml|
|Immunoprecipitation (IP)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
CD10 (neutral endopeptidase - NEP, common acute lymphocytic leukemia antigen - CALLA, membrane metallo-endopeptidase - MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Utilility of flow cytometry as ancillary study to improve the cytologic diagnosis of thyroid lymphomas.
MA1-19086 was used in flow cytometry to assess the efficacy of using flow cytometry immunophenotyping with fine-needle aspiration cytology for the diagnosis of thyroid lymphoma.
|Stacchini A,Pacchioni D,Demurtas A,Aliberti S,Cassenti A,Isolato G,Gazzera C,Veltri A,Sapino A,Papotti M,Freddi M,Palestini N,Sisto G,Novero D||Cytometry. Part B, Clinical cytometry (88:320)||2015|
Flow cytometry significantly improves the diagnostic value of fine needle aspiration cytology of lymphoproliferative lesions of salivary glands.
MA1-19086 was used in flow cytometry to compare fine needle aspiration cytology with flow cytometry immunophenotyping for the diagnosis of lymphoproliferative processes in the salivary glands.
|Stacchini A,Aliberti S,Pacchioni D,Demurtas A,Isolato G,Gazzera C,Veltri A,Maletta F,Molinaro L,Novero D||Cytopathology : official journal of the British Society for Clinical Cytology (25:231)||2014|
|Not Applicable||Not Cited||
Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis.
MA1-19086 was used in flow cytometry to identify Staphopain A as a chemokine receptor blocker of CXCR2
|Laarman AJ,Mijnheer G,Mootz JM,van Rooijen WJ,Ruyken M,Malone CL,Heezius EC,Ward R,Milligan G,van Strijp JA,de Haas CJ,Horswill AR,van Kessel KP,Rooijakkers SH||The EMBO journal (31:3607)||2012|
Atriopeptidase; CALLA; CD10; Common acute lymphocytic leukemia antigen; Enkephalinase; membrane metallo-endopeptidase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase neutral endopeptidase; membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; NEP; Neprilysin; neprilysin-390; neprilysin-411; Neutral endopeptidase 24.11; SFE; Skin fibroblast elastase
CALLA; CD10; CMT2T; EPN; MME; NEP; SFE