|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues G(147) K N E D G K G R C P F(158) of human CD100.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4201 detects CD100 in human samples.
PA1-4201 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~158 kDa protein representing CD100 in transfected CHO cells.
The PA1-4201 immunogen is a synthetic peptide corresponding to residues G(147) K N E D G K G R C P F(158) of human CD100.
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100 is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B-cell signaling by augmenting B-cell aggregation and survival and down-regulating CD23 expression. CD72 is a lymphocyte receptor for the Class IV semaphorin CD100, which is involved in regulating B cell signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.