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Invitrogen
Applications | Tested Dilution | Publications |
---|---|---|
Flow Cytometry (Flow) |
20 µL/1x10^6 cells | View 3 publications 3 publications |
Product Specifications | |
---|---|
Species Reactivity |
Human, Rat |
Published species |
Human |
Host/Isotype |
Mouse / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
MEM-226 |
Immunogen |
Recombinant vaccinia virus containing the human CD105 cDNA. |
Conjugate |
FITC
|
Excitation/Emission Max |
498/517 nm View spectra |
Form |
Liquid |
Purification |
Size-exclusion chromatography |
Storage buffer |
PBS, pH 7.4, with 0.2% BSA |
Contains |
15mM sodium azide |
Storage conditions |
4° C, store in dark, DO NOT FREEZE! |
RRID |
AB_1071125 |
CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.
Protein Aliases: CD105; CD105 antigen; Endoglin; ORW
Gene Aliases: END; ENG; HHT1; ORW1
UniProt ID: (Human) P17813
Entrez Gene ID: (Human) 2022, (Rat) 497010
Molecular Function:
transmembrane signal receptor
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