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      CD11c Monoclonal Antibody (3.9), PE

      See 83 other CD11c antibodies ›
      CD11c Monoclonal Antibody, PE conjugate for Flow

      Catalog#: A18674 Invitrogen

      Catalog # Size Price (USD) Qty Datasheet
      A18674 25 tests
      93.25
      Please enter a quantity in the range of 1 to 199.
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      Product Details

      References

      Bioinformatics

      Documents
      Details
      Tested species reactivity Human
      Published species reactivity Not Applicable
      Host / Isotype Mouse / IgG1, kappa
      Class Monoclonal
      Type Antibody
      Clone 3.9
      Immunogen Synovial cells and human monocytes.
      Conjugate PE
      Form Liquid
      Concentration 0.2 mg/ml
      Purification purified
      Storage buffer PBS, pH 7.2, with 0.1% gelatin
      Contains 0.09% sodium azide
      Storage Conditions 4° C
      Tested Applications Dilution *
      Flow Cytometry (Flow) 1 µg/test

      * Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.

      Published Applications
      Flow Cytometry (Flow) See 3 publications below

      Background/Target Information

      ITGAX is the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

      For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

      References

      Flow Cytometry

      Species Dilution Title Authors Journal (Vol:Pg) Year
      Not Applicable Not Cited A six-color flow cytometric assay for the analysis of peripheral blood dendritic cells.
      A18674 was used in flow cytometry to develop a 6-color assay to identify dendritic cells       		Giannelli S,Taddeo A,Presicce P,Villa ML,Della Bella S Cytometry. Part B, Clinical cytometry (74:349) 2008
      Not Applicable Not Cited Filarial antigens impair the function of human dendritic cells during differentiation.
      A18674 was used in flow cytometry to assess the effect of microfilariae antigen on dendritic cells       		Semnani RT,Sabzevari H,Iyer R,Nutman TB Infection and immunity (69:5813) 2001
      Not Applicable Not Cited Isolation and characterization of rhesus blood dendritic cells using flow cytometry.
      A18674 was used in flow cytometry to determine the phenotype and function of isolated rhesus peripheral blood dendritic cells       		Pichyangkul S,Saengkrai P,Yongvanitchit K,Limsomwong C,Gettayacamin M,Walsh DS,Stewart VA,Ballou WR,Heppner DG Journal of immunological methods (252:15) 2001

      Bioinformatics

      Protein Aliases:

      AI449405; CD11 antigen-like family member C; CD11c; complement component 3 receptor 4 subunit; Cr4; integrin alpha X; Integrin alpha-X; integrin aX; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); ITGAX; Leu M5; leu M5, alpha subunit; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; leukocyte surface antigen p150,95, alpha subunit; myeloid membrane antigen, alpha subunit; N418; p150 95 integrin alpha chain

      Gene Aliases:

      CD11C; ITGAX; SLEB6

      UniProt ID:

      (Human) P20702

      Entrez Gene ID:

      (Human) 3687

      Function(s) Process(es)

      Documents

      Material safety data sheets (MSDS)

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