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Invitrogen
CD131 (CSF2RB) (Trabikibart Biosimilar) Recombinant Human Monoclonal Antibody
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CD131 (CSF2RB) (Trabikibart Biosimilar) Antibody (MA5-58863) in Flow
Flow cytometry analysis of CD131 (CSF2RB) (Trabikibart Biosimilar) Recombinant monoclonal antibody (Product # MA5-58863). Human CSF2RB HEK293 cells were stained with (CSL311) and negative control protein respectively, washed and then followed by PE and analyzed with FACS, EC50=0.049 µg/mL.
Product Details
MA5-58863
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG4SP
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
25mM histidine, pH 6.2, with 0.01% Tween 80, 8% sucrose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Product Specific Information
For reconstitution, add sterile, distilled water to achieve a final antibody concentration of 1 mg/mL. Gently shake to solubilize the protein completely. Do not vortex. Reconstituted products should be stored at -80 °.
Target Information
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta common cytokine receptor; beta-GM-CSF receptor; CD antigen CD131; CD131; CDw131; colony stimulating factor 2 receptor beta common subunit; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); colony-stimulating factor-2 receptor, beta, low-affinity; CSF2RB; Cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL-3 RB; IL-3 Receptor beta; IL3R beta; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); unnamed protein product
Gene Aliases: betaGMR; CD131; CDw131; CSF2RB; IL3RB; IL5RB; SMDP5
UniProt ID: (Human) P32927
Entrez Gene ID: (Human) 1439
signal transduction
JAK-STAT cascade
respiratory gaseous exchange
immunoglobulin mediated immune response
cytokine-mediated signaling pathway
response to lipopolysaccharide
cellular response to interleukin-3
interleukin-5-mediated signaling pathway
interleukin-3-mediated signaling pathway
granulocyte-macrophage colony-stimulating factor signaling pathway
positive regulation of leukocyte proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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