|Flow Cytometry (Flow)||2.0 ug/10^6 cells|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rat / IgG1|
|Immunogen||Recombinant mouse OX-40 antigen|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17915 targets CD134/OX-40 in FACS applications and shows reactivity with Mouse samples.
The MA5-17915 immunogen is recombinant mouse OX-40 antigen.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD134; cluster designation 134; OX40 antigen; OX40L receptor; tax-transcriptionally activated glycoprotein 1; TNFRSF4; Tumor necrosis factor receptor superfamily member 4
Gene Aliases: ACT35; CD134; Ly-70; Ox40; Tnfrsf4; Txgp1; TXGP1L
UniProt ID: (Mouse) P47741
Entrez Gene ID: (Mouse) 22163
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