|Tested species reactivity||Mouse|
|Host / Isotype||Rat / IgG1|
|Immunogen||Recombinant mouse OX-40 antigen.|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 ug/1 million cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-70087 detects CD134 in mouse samples.
MA1-70087 has been successfully used in flow cytometry procedures.
The MA1-70087 immunogen is recombinant mouse OX-40 antigen.
CD134, also known as OX40, is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary costimulatory molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.