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|Tested species reactivity||Mouse|
|Host / Isotype||Rat / IgG1|
|Immunogen||Recombinant mouse OX-40 antigen.|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 ug/1 million cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-70087 detects CD134 in mouse samples.
MA1-70087 has been successfully used in flow cytometry procedures.
The MA1-70087 immunogen is recombinant mouse OX-40 antigen.
CD134, also known as OX40, is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary costimulatory molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cluster designation 134; OX40 antigen; OX40L receptor; tax-transcriptionally activated glycoprotein 1; TNFRSF4; tumor necrosis factor receptor superfamily member 4
ACT35; CD134; Ly-70; Ox40; Tnfrsf4; Txgp1; TXGP1L