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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Protein A-CR purified soluble recombinant form of CD147, CD147Rg.|
|Storage buffer||PBS with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||20ul x 100ul whole blood or 10^6 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
This antibody recognizes an epitope in the N-terminal Ig domain (D1) of CD147 (Neurothelin), a 50-60 kDa type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes.
This is a high-affinity antibody capable of binding to unstimulated peripheral blood T cells.
CD147 (basigin, neurothelin, OX-47, 5A11, CE9, M6) also known as EMMPRIN (extracellular matrix metalloproteinase inducer) or TCSF (tumour cell-derived collagenase-stimulatory factor) is an ubiquitously expressed cell surface protein with multiple glycosylated forms. The highest level of CD147 expression is on metabolically active cells, such as lymphoblasts, inflammatory cells, brown adipocytes and malignant tumour cells. CD147 has multiple functions, including facilitating of cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulation of integrin functions, it plays roles in cell development and activation, fetal development or retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Multiple heparan sulfate binding site engagements are required for the infectious entry of human papillomavirus type 16.
MA1-19588 was used in immunocytochemistry to study the infectious entry of HPV16 and the role of heparin binding sites
|Richards KF,Bienkowska-Haba M,Dasgupta J,Chen XS,Sapp M||Journal of virology (87:11426)||2013|
basigin; CD147; CD147 antigen; collagenase stimulatory factor; EMMPRIN; extracellular matrix metalloproteinase inducer; leukocyte activation antigen M6; M6; OK; OK blood group antigen; TCSF; tumor cell-derived collagenase stimulatory factor
5F7; BSG; CD147; EMMPRIN; OK; TCSF; UNQ6505/PRO21383