Product References
An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancer.
Cell reports. Medicine
Johnson BE,Creason AL,Stommel JM,Keck JM,Parmar S,Betts CB,Blucher A,Boniface C,Bucher E,Burlingame E,Camp T,Chin K,Eng J,Estabrook J,Feiler HS,Heskett MB,Hu Z,Kolodzie A,Kong BL,Labrie M,Lee J,Leyshock P,Mitri S,Patterson J,Riesterer JL,Sivagnanam S,Somers J,Sudar D,Thibault G,Weeder BR,Zheng C,Nan X,Thompson RF,Heiser LM,Spellman PT,Thomas G,Demir E,Chang YH,Coussens LM,Guimaraes AR,Corless C,Goecks J,Bergan R,Mitri Z,Mills GB,Gray JW
MA5-11458 was used in Immunohistochemistry to present illustrative examples of how integrative analyses of data reveal potential mechanisms of response and resistance and suggest novel therapeutic vulnerabilities.
Tue Feb 15 00:00:00 EST 2022
Pancreatic cancer cells render tumor-associated macrophages metabolically reprogrammed by a GARP and DNA methylation-mediated mechanism.
Signal transduction and targeted therapy
Zhang M,Pan X,Fujiwara K,Jurcak N,Muth S,Zhou J,Xiao Q,Li A,Che X,Li Z,Zheng L
MA5-11458 was used immunohistochemistry (paraffin) suggest that PDA cells are able to reprogram M1-like macrophages metabolically and functionally through a GARP-dependent and DNA methylation-mediated mechanism to adopt a pro-cancerous fate.
Fri Oct 29 00:00:00 EDT 2021
Pancreatic cancer cells render tumor-associated macrophages metabolically reprogrammed by a GARP and DNA methylation-mediated mechanism.
Signal transduction and targeted therapy
Zhang M,Pan X,Fujiwara K,Jurcak N,Muth S,Zhou J,Xiao Q,Li A,Che X,Li Z,Zheng L
MA5-11458 was used immunohistochemistry (paraffin) suggest that PDA cells are able to reprogram M1-like macrophages metabolically and functionally through a GARP-dependent and DNA methylation-mediated mechanism to adopt a pro-cancerous fate.
Fri Oct 29 00:00:00 EDT 2021
Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques.
Cell
Aid M,Busman-Sahay K,Vidal SJ,Maliga Z,Bondoc S,Starke C,Terry M,Jacobson CA,Wrijil L,Ducat S,Brook OR,Miller AD,Porto M,Pellegrini KL,Pino M,Hoang TN,Chandrashekar A,Patel S,Stephenson K,Bosinger SE,Andersen H,Lewis MG,Hecht JL,Sorger PK,Martinot AJ,Estes JD,Barouch DH
Published figure using CD163 monoclonal antibody (Product # MA5-11458) in Immunocytochemistry
Wed Nov 25 00:00:00 EST 2020
Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques.
Cell
Aid M,Busman-Sahay K,Vidal SJ,Maliga Z,Bondoc S,Starke C,Terry M,Jacobson CA,Wrijil L,Ducat S,Brook OR,Miller AD,Porto M,Pellegrini KL,Pino M,Hoang TN,Chandrashekar A,Patel S,Stephenson K,Bosinger SE,Andersen H,Lewis MG,Hecht JL,Sorger PK,Martinot AJ,Estes JD,Barouch DH
Published figure using CD163 monoclonal antibody (Product # MA5-11458) in Immunocytochemistry
Wed Nov 25 00:00:00 EST 2020
Amplification of transglutaminase 2 enhances tumor-promoting inflammation in gastric cancers.
Experimental & molecular medicine
Cho SY,Oh Y,Jeong EM,Park S,Lee D,Wang X,Zeng Q,Qin H,Hu F,Gong H,Liu X,Zhang G,Na D,Lee J,Chae J,Suh YS,Kong SH,Lee HJ,Kim JI,Park H,Zhang C,Yang HK,Lee C
MA5-11458 was used in Immunohistochemistry to show transglutaminase 2 is a regulator of the gastric cancer microenvironment.
Fri May 01 00:00:00 EDT 2020
The interferon-gamma pathway is selectively up-regulated in the liver of patients with secondary hemophagocytic lymphohistiocytosis.
PloS one
Prencipe G,Bracaglia C,Caiello I,Pascarella A,Francalanci P,Pardeo M,Meneghel A,Martini G,Rossi MN,Insalaco A,Marucci G,Nobili V,Spada M,Zulian F,De Benedetti F
MA5-11458 was used in Immunohistochemistry to investigate the activation of the IFN-gamma pathway in sHLH livers.
Mon Apr 06 00:00:00 EDT 2020
The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell-mediated resistance to metastasis.
Nature immunology
Mattiola I,Tomay F,De Pizzol M,Silva-Gomes R,Savino B,Gulic T,Doni A,Lonardi S,Astrid Boutet M,Nerviani A,Carriero R,Molgora M,Stravalaci M,Morone D,Shalova IN,Lee Y,Biswas SK,Mantovani G,Sironi M,Pitzalis C,Vermi W,Bottazzi B,Mantovani A,Locati M
MA5-11458 was used in Immunohistochemistry to investigate the expression and function in macrophages of the plasma membrane tetraspan molecule MS4A4A.
Thu Aug 01 00:00:00 EDT 2019
Poor Response to Neoadjuvant Chemotherapy Correlates with Mast Cell Infiltration in Inflammatory Breast Cancer.
Cancer immunology research
Reddy SM,Reuben A,Barua S,Jiang H,Zhang S,Wang L,Gopalakrishnan V,Hudgens CW,Tetzlaff MT,Reuben JM,Tsujikawa T,Coussens LM,Wani K,He Y,Villareal L,Wood A,Rao A,Woodward WA,Ueno NT,Krishnamurthy S,Wargo JA,Mittendorf EA
MA5-11458 was used in Immunohistochemistry to highlight the strong association of mast cell infiltration with poor response to NAC, suggesting a mechanism of treatment resistance and a potential therapeutic target in IBC.
Sat Jun 01 00:00:00 EDT 2019
Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets.
Cancer cell
Cassetta L,Fragkogianni S,Sims AH,Swierczak A,Forrester LM,Zhang H,Soong DYH,Cotechini T,Anur P,Lin EY,Fidanza A,Lopez-Yrigoyen M,Millar MR,Urman A,Ai Z,Spellman PT,Hwang ES,Dixon JM,Wiechmann L,Coussens LM,Smith HO,Pollard JW
MA5-11458 was used in Immunohistochemistry to show that monocyte subpopulation distribution and transcriptomes are significantly altered by the presence of endometrial and breast cancer.
Mon Apr 15 00:00:00 EDT 2019
Lung and Heart Injury in a Nonhuman Primate Model of Partial-body Irradiation with Minimal Bone Marrow Sparing: Histopathological Evidence of Lung and Heart Injury.
Health physics
Parker GA,Li N,Takayama K,Farese AM,MacVittie TJ
MA5-11458 was used in Immunohistochemistry to show that delayed radiation-associated changes in the heart consisted primarily of myocardial fibrosis, with rare histological evidence of myofiber degeneration.
Fri Mar 01 00:00:00 EST 2019
Accumulation of follicular CD8+ T cells in pathogenic SIV infection.
The Journal of clinical investigation
Ferrando-Martinez S,Moysi E,Pegu A,Andrews S,Nganou Makamdop K,Ambrozak D,McDermott AB,Palesch D,Paiardini M,Pavlakis GN,Brenchley JM,Douek D,Mascola JR,Petrovas C,Koup RA
Published figure using CD163 monoclonal antibody (Product # MA5-11458) in Immunohistochemistry
Tue May 01 00:00:00 EDT 2018
Accumulation of follicular CD8+ T cells in pathogenic SIV infection.
The Journal of clinical investigation
Ferrando-Martinez S,Moysi E,Pegu A,Andrews S,Nganou Makamdop K,Ambrozak D,McDermott AB,Palesch D,Paiardini M,Pavlakis GN,Brenchley JM,Douek D,Mascola JR,Petrovas C,Koup RA
Published figure using CD163 monoclonal antibody (Product # MA5-11458) in Immunohistochemistry
Tue May 01 00:00:00 EDT 2018
Systemic HIV-1 infection produces a unique glial footprint in humanized mouse brains.
Disease models & mechanisms
Li W,Gorantla S,Gendelman HE,Poluektova LY
MA5-11458 was used in Immunohistochemistry to create a mouse model of neuroAIDS that can facilitate diagnostic, therapeutic and viral eradication strategies for an infected nervous system.
Tue Dec 19 00:00:00 EST 2017
An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition.
The Journal of experimental medicine
Young HL,Rowling EJ,Bugatti M,Giurisato E,Luheshi N,Arozarena I,Acosta JC,Kamarashev J,Frederick DT,Cooper ZA,Reuben A,Gil J,Flaherty KT,Wargo JA,Vermi W,Smith MP,Wellbrock C,Hurlstone A
MA5-11458 was used in Immunohistochemistry to conclude that melanoma inflammatory niches adapt to and confer drug tolerance toward BRAF and MEK inhibitors early during treatment.
Mon Jun 05 00:00:00 EDT 2017
Macrophage migration inhibitory factor protects from nonmelanoma epidermal tumors by regulating the number of antigen-presenting cells in skin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Brocks T,Fedorchenko O,Schliermann N,Stein A,Moll UM,Seegobin S,Dewor M,Hallek M,Marquardt Y,Fietkau K,Heise R,Huth S,Pfister H,Bernhagen J,Bucala R,Baron JM,Fingerle-Rowson G
MA511458 was used in immunohistochemistry - paraffin section to propose a tumor-suppressive activity for macrophage migration inhibitory factor in murine skin
Wed Feb 01 00:00:00 EST 2017
Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists.
Scientific reports
Ang Z,Er JZ,Tan NS,Lu J,Liou YC,Grosse J,Ding JL
Published figure using CD163 monoclonal antibody (Product # MA5-11458) in Immunohistochemistry
Mon Sep 26 00:00:00 EDT 2016
Autocrine IL-10 activation of the STAT3 pathway is required for pathological macrophage differentiation in polycystic kidney disease.
Disease models & mechanisms
Peda JD,Salah SM,Wallace DP,Fields PE,Grantham CJ,Fields TA,Swenson-Fields KI
Published figure using CD163 monoclonal antibody (Product # MA5-11458) in Immunohistochemistry
Thu Sep 01 00:00:00 EDT 2016
Autocrine IL-10 activation of the STAT3 pathway is required for pathological macrophage differentiation in polycystic kidney disease.
Disease models & mechanisms
Peda JD,Salah SM,Wallace DP,Fields PE,Grantham CJ,Fields TA,Swenson-Fields KI
Published figure using CD163 monoclonal antibody (Product # MA5-11458) in Immunohistochemistry
Thu Sep 01 00:00:00 EDT 2016
The Prognostic Significance of pSTAT1 and CD163 Expressions in Surgically Resected Stage 1 Pulmonary Squamous Cell Carcinomas.
Annals of surgical oncology
Lin MW,Yang CY,Kuo SW,Wu CT,Chang YL,Yang PC
MA511458 was used in immunohistochemistry - paraffin section to examine the association between tumor-associated macrophage polarization and clinical outcomes for early-stage pulmonary squamous cell carcinoma
Thu Sep 01 00:00:00 EDT 2016
A 2-Step Laemmli and Antigen Retrieval Method Improves Immunodetection.
Applied immunohistochemistry & molecular morphology : AIMM
Scalia CR,Gendusa R,Cattoretti G
MA511458 was used in immunohistochemistry - paraffin section to develop an "antigen relaxing" method to improve routine detection of scarce antigens in formalin-fixed, paraffin-embedded material
Fri Jul 01 00:00:00 EDT 2016
Dendritic cell-derived VEGF-A plays a role in inflammatory angiogenesis of human secondary lymphoid organs and is driven by the coordinated activation of multiple transcription factors.
Oncotarget
Salvi V,Vermi W,Gianello V,Lonardi S,Gagliostro V,Naldini A,Sozzani S,Bosisio D
MA511458 was used in immunohistochemistry - paraffin section to report that human CD11c positive cells are the main VEGF-A-producing cell population in reactive secondary lymphoid organs
Tue Jun 28 00:00:00 EDT 2016
Expression of Activated Ras in Gastric Chief Cells of Mice Leads to the Full Spectrum of Metaplastic Lineage Transitions.
Gastroenterology
Choi E,Hendley AM,Bailey JM,Leach SD,Goldenring JR
MA5-11458 was used in immunohistochemistry - paraffin section to test the expression of activated Ras in gastric chief cells in mice and the metaplastic lineage transitions
Fri Apr 01 00:00:00 EDT 2016
T helper 2 polarization in senile erythroderma with elevated levels of TARC and IgE.
Dermatology (Basel, Switzerland)
Nakano-Tahara M,Terao M,Nishioka M,Kitaba S,Murota H,Katayama I
MA5-11458 was used in immunohistochemistry - paraffin section to identify features to distinguish senile erythroderma from senile atopic dermatitis
Thu Sep 10 00:00:00 EDT 2015
Rapid reconstitution of functionally active 6-sulfoLacNAc(+) dendritic cells (slanDCs) of donor origin following allogeneic haematopoietic stem cell transplant.
Clinical and experimental immunology
Mimiola E,Marini O,Perbellini O,Micheletti A,Vermi W,Lonardi S,Costantini C,Meneghelli E,Andreini A,Bonetto C,Vassanelli A,Cantini M,Zoratti E,Massi D,Zamo' A,Leso A,Quaresmini G,Benedetti F,Pizzolo G,Cassatella MA,Tecchio C
MA5-11458 was used in western blot to study the reconstitution and function of donor slan-dendritic cells following allogeneic hematopoietic stem cell transplantation
Wed Oct 01 00:00:00 EDT 2014
Occurrence of nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects.
PloS one
Lorenzi L,Tabellini G,Vermi W,Moratto D,Porta F,Notarangelo LD,Patrizi O,Sozzani S,de Saint Basile G,Latour S,Pace D,Lonardi S,Facchetti F,Badolato R,Parolini S
MA5-11458 was used in immunohistochemistry to study factors associated with nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome
Wed Oct 01 00:00:00 EDT 2014
Clinical significance of sIL-2R levels in B-cell lymphomas.
PloS one
Yoshida N,Oda M,Kuroda Y,Katayama Y,Okikawa Y,Masunari T,Fujiwara M,Nishisaka T,Sasaki N,Sadahira Y,Mihara K,Asaoku H,Matsui H,Seto M,Kimura A,Arihiro K,Sakai A
MA5-11458 was used in immunohistochemistry to study the clinical value of soluble IL-2 receptor levels in B-cell lymphomas
Tue Sep 02 00:00:00 EDT 2014
CD8-predominant T-cell CNS infiltration accompanies GVHD in primates and is improved with immunoprophylaxis.
Blood
Kaliyaperumal S,Watkins B,Sharma P,Furlan S,Ramakrishnan S,Giver C,Garcia A,Courtney C,Knight H,Strobert E,Elder E,Crenshaw T,Blazar BR,Waller EK,Westmoreland S,Kean LS
MA5-11458 was used in immunohistochemistry - paraffin section to report that CD8-predominant T-cell central nervous system infiltration accompanies graft verse host disease in primates and improves with immunoprophylaxis
Thu Mar 20 00:00:00 EDT 2014
Diagnostic and therapeutic strategy and the most efficient prognostic factors of breast malignant fibrous histiocytoma.
Scientific reports
Qiu SQ,Wei XL,Huang WH,Wu MY,Qin YS,Li YK,Zhang GJ
MA5-11458 was used in immunohistochemistry - paraffin section to report the clinicopathological features of 9 breast malignant fibrous histiocytoma patients
Fri Feb 14 00:00:00 EST 2014
Blastic plasmacytoid dendritic cell neoplasm with leukemic presentation: an Italian multicenter study.
Haematologica
Pagano L,Valentini CG,Pulsoni A,Fisogni S,Carluccio P,Mannelli F,Lunghi M,Pica G,Onida F,Cattaneo C,Piccaluga PP,Di Bona E,Todisco E,Musto P,Spadea A,D'Arco A,Pileri S,Leone G,Amadori S,Facchetti F
MA5-11458 was used in immunohistochemistry to evaluate 43 cases of blastic plasmacytoid dendritic cell neoplasm with leukemic presentation
Fri Feb 01 00:00:00 EST 2013
Intravascular large B-cell lymphoma with hemophagocytic syndrome (Asian variant) in a Caucasian patient.
International journal of clinical and experimental pathology
Fung KM,Chakrabarty JH,Kern WF,Magharyous H,Gehrs BC,Li S
MA5-11458 was used in immunohistochemistry to report on a case of intravascular large B-cell lymphoma with hemophagocytic syndrome (Asian variant) in a Caucasian patient
Tue Dec 11 00:00:00 EST 2012
Malignant fibrous histiocytoma and fibrosarcoma of bone: a re-assessment in the light of currently employed morphological, immunohistochemical and molecular approaches.
Virchows Archiv : an international journal of pathology
Romeo S,Bovée JV,Kroon HM,Tirabosco R,Natali C,Zanatta L,Sciot R,Mertens F,Athanasou N,Alberghini M,Szuhai K,Hogendoorn PC,Dei Tos AP
MA5-11458 was used in immunohistochemistry to study the classification of malignant fibrous histiocytoma and fibrosarcoma of bone
Thu Nov 01 00:00:00 EDT 2012
Alternative activation of macrophages in rhesus macaques (Macaca mulatta) with endometriosis.
Comparative medicine
Smith KA,Pearson CB,Hachey AM,Xia DL,Wachtman LM
MA5-11458 was used in immunohistochemistry to investigate rhesus macaque macrophage activation during endometriosis
Wed Aug 01 00:00:00 EDT 2012
Temporal differences of onset between primary skin lesions and regional lymph node lesions for tularemia in Japan: a clinicopathologic and immunohistochemical study of 19 skin cases and 54 lymph node cases.
Virchows Archiv : an international journal of pathology
Asano S,Mori K,Yamazaki K,Sata T,Kanno T,Sato Y,Kojima M,Fujita H,Akaike Y,Wakasa H
MA5-11458 was used in immunohistochemistry to study skin lesions and lymph node lesions and their mutual relation over time in tularemia
Fri Jun 01 00:00:00 EDT 2012
Immunophenotypic alterations in resident immune cells and myocardial fibrosis in the aging rhesus macaque (Macaca mulatta) heart.
Toxicologic pathology
Macri SC,Bailey CC,de Oca NM,Silva NA,Rosene DL,Mansfield KG,Miller AD
MA5-11458 was used in immunohistochemistry to study changes in immune cell immunophenotype with myocardial fibrosis in the aging rhesus macaque heart
Fri Jun 01 00:00:00 EDT 2012
Use of classic and novel immunohistochemical markers in the diagnosis of cutaneous myeloid sarcoma.
Journal of cutaneous pathology
Amador-Ortiz C,Hurley MY,Ghahramani GK,Frisch S,Klco JM,Lind AC,Nguyen TT,Hassan A,Kreisel FH,Frater JL
MA5-11458 was used in immunohistochemistry to study the use of classic and novel immunohistochemical markers in the diagnosis of cutaneous myeloid sarcoma
Thu Dec 01 00:00:00 EST 2011
Tumor-associated macrophages as major source of APRIL in gastric MALT lymphoma.
Blood
Munari F,Lonardi S,Cassatella MA,Doglioni C,Cangi MG,Amedei A,Facchetti F,Eishi Y,Rugge M,Fassan M,de Bernard M,D'Elios MM,Vermi W
MA5-11458 was used in immunohistochemistry to identify the lymphomagenesis-promoting cytokine
Thu Jun 16 00:00:00 EDT 2011
Cellular neurothekeoma with fascicular growth features mimicking cellular dermatofibroma.
The American Journal of dermatopathology
Thakral B,Gleason BC,Thomas AB,Billings SD,Victor TA,Cibull TL
MA5-11458 was used in immunohistochemistry to characterize and compare cellular neurothekeoma and dermatofibroma
Sun May 01 00:00:00 EDT 2011
Extraintestinal Crohn's disease mimicking autoimmune inner ear disease: a histopathological approach.
Audiology & neuro-otology
Dettmer M,Hegemann I,Hegemann SC
MA5-11458 was used in immunohistochemistry to study the histopathology of a patient with extraintestinal Crohn's disease mimicking autoimmune inner ear disease
Fri Mar 25 00:00:00 EDT 2011
Synovial immunopathology in haemochromatosis arthropathy.
Annals of the rheumatic diseases
Heiland GR,Aigner E,Dallos T,Sahinbegovic E,Krenn V,Thaler C,Weiss G,Distler JH,Datz C,Schett G,Zwerina J
MA5-11458 was used in immunohistochemistry to investigate the pathophysiology of musculoskeletal tissues in haemochromatosis arthropathy
Tue Jun 01 00:00:00 EDT 2010
Human peripheral lymphoid tissues contain autoimmune regulator-expressing dendritic cells.
The American journal of pathology
Poliani PL,Kisand K,Marrella V,Ravanini M,Notarangelo LD,Villa A,Peterson P,Facchetti F
MA5-11458 was used in immunohistochemistry to study the presence of dendritic cells expressing autoimmune regulator in peripheral lymphoid tissue in humans
Mon Mar 01 00:00:00 EST 2010
Increased T-bet+ cytotoxic effectors and type I interferon-mediated processes in chronic graft-versus-host disease of the oral mucosa.
Blood
Imanguli MM,Swaim WD,League SC,Gress RE,Pavletic SZ,Hakim FT
MA5-11458 was used in immunohistochemistry to investigate the pathogenesis of chronic graft-versus-host disease
Thu Apr 09 00:00:00 EDT 2009
Frequent expression of the novel cancer testis antigen MAGE-C2/CT-10 in hepatocellular carcinoma.
International journal of cancer
Riener MO,Wild PJ,Soll C,Knuth A,Jin B,Jungbluth A,Hellerbrand C,Clavien PA,Moch H,Jochum W
MA5-11458 was used in immunohistochemistry - paraffin section to ascertain the expression of several cancer testis antigens in hepatocellular carcinomas, intrahepatic cholangiocarcinomas, extrahepatic cholangiocarcinomas, and gallbladder carcinomas
Thu Jan 15 00:00:00 EST 2009
Increased number of islet-associated macrophages in type 2 diabetes.
Diabetes
Ehses JA,Perren A,Eppler E,Ribaux P,Pospisilik JA,Maor-Cahn R,Gueripel X,Ellingsgaard H,Schneider MK,Biollaz G,Fontana A,Reinecke M,Homo-Delarche F,Donath MY
MA5-11458 was used in immunohistochemistry to examine the status of islet-associated macrophages in type 2 diabetes
Sat Sep 01 00:00:00 EDT 2007
Phenotypic variation in myocardial macrophage populations suggests a role for macrophage activation in SIV-associated cardiac disease.
AIDS research and human retroviruses
Yearley JH,Pearson C,Shannon RP,Mansfield KG
MA5-11458 was used in immunohistochemistry to study the role of macrophage activation in SIV-associated cardiac disease
Sun Apr 01 00:00:00 EDT 2007
Hemophagocytic macrophages constitute a major compartment of heme oxygenase expression in sepsis.
European journal of haematology
Schaer DJ,Schaer CA,Schoedon G,Imhof A,Kurrer MO
MA5-11458 was used in immunohistochemistry to investigate the mechanism for the increase of heme oxygenase expression in sepsis
Wed Nov 01 00:00:00 EST 2006
serine protease
