This antibody shows approximately 50% cross-reactivity with recombinant mouse OCAM and no cross-reactivity with recombinant human (rh) BCAM, rhEpCAM, rhMCAM, or rhNCAM-L1.
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
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Protein Aliases: Activated leukocyte cell adhesion molecule; CD166; CD166 antigen; FLJ38514; MGC71733
Gene Aliases: ALCAM; CD166; MEMD
UniProt ID: (Human) Q13740
Entrez Gene ID: (Human) 214