Rat anti Mouse CD169 antibody, clone 3D6.112 recognizes mouse CD169 also known as sialoadhesin, Sheep erythrocyte receptor or Siglec-1.
The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions. Family members include sialoadhesin, CD22 and CD33. Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.
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Protein Aliases: CD169; SER; Sheep erythrocyte receptor; Sialic acid-binding Ig-like lectin 1; Sialoadhesin; Siglec-1
Gene Aliases: Cd169; Sa; Siglec-1; Siglec1; Sn
UniProt ID: (Mouse) Q62230
Entrez Gene ID: (Mouse) 20612