|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgM|
|Storage buffer||PBS with 0.2% BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4°C or -20°C if preferred, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Neat|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
For FACS analysis, use 20ul of the suggested working dilution to label 5x10^5 cells in 100ul.
CD16 (also known low affinity Fc gamma receptor III for IgG (FcgammaRIII) or Leu 11) exists as a polypepetide-anchored from (FCgammaRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcgammaRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2. CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.