Invitrogen
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1 µg/mL | View 1 publication 1 publication |
Immunohistochemistry (IHC) |
- | View 7 publications 7 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100 | - |
Flow Cytometry (Flow) |
- | View 2 publications 2 publications |
ELISA (ELISA) |
- | View 1 publication 1 publication |
Immunoprecipitation (IP) |
2 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Published species |
Human |
Host/Isotype |
Mouse / IgG1, kappa |
Class |
Monoclonal |
Type |
Antibody |
Clone |
UJ127 |
Immunogen |
Homogenous suspension of 16 week human fetal brain |
Conjugate |
Biotin
|
Form |
Liquid |
Concentration |
0.2 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS, pH 7.4, with 0.2% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
4° C |
RRID |
AB_10990347 |
MA5-14137 targets L1 Cell Adhesion Molecule in IHC (P), IP, and WB applications and shows reactivity with Human samples.
The MA5-14137 immunogen is homogenous suspension of 16 week human fetal brain.
L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: antigen identified by monoclonal antibody R1; CD 171; CD171; CD171 molecule; N-CAM-L1; Neural cell adhesion molecule L1; sCD171; sL1 CAM; sL1CAM; soluble CD 171; soluble CD171; soluble L1 CAM; soluble L1CAM
Gene Aliases: CAML1; CD171; HSAS; HSAS1; L1CAM; MASA; MIC5; N-CAM-L1; N-CAML1; NCAM-L1; S10; SPG1
UniProt ID: (Human) P32004
Entrez Gene ID: (Human) 3897
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