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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||15mM sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
The frequencies of human neutrophil alloantigens in the Chinese Han population of Guangzhou.
A15743 was used in flow cytometry to report the frequencies of human neutrophil antigens in the major Han ethnic group living in China.
|Xia W,Bayat B,Sachs U,Chen Y,Shao Y,Xu X,Deng J,Ding H,Fu Y,Ye X,Santoso S||Transfusion (51:1271)||2011|
CD177; CD177 antigen; cell surface receptor; HNA-2a; HNA2A; Human neutrophil alloantigen 2a; NB1; NB1 glycoprotein; NB1 GP; polycythemia rubra vera 1; Polycythemia rubra vera protein 1; PRV-1; PRV1
CD177; HNA-2a; HNA2A; NB1; NB1 GP; PRV-1; PRV1; UNQ595/PRO1181