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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 130 and 213 of Human IGLL1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-29712 targets IGLL1 in WB applications and shows reactivity with Human samples.
The PA5-29712 immunogen is synthetic peptide corresponding to a region within amino acids 130 and 213 of Human IGLL1.
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
14.1; AGM2; CD179 antigen-like family member B; CD179b; CD179b antigen; Ig lambda-5; IGL1; IGL5; IGLJ14.1; IGLL; IGO; IGVPB; Immunoglobulin lambda-like polypeptide 1; Immunoglobulin omega polypeptide; immunoglobulin omega polypeptide chain; immunoglobulin-related 14.1 protein; Immunoglobulin-related protein 14.1; lambda5; Pre-B lymphocyte-specific protein-2; VPREB2
14.1; AGM2; CD179b; IGL1; IGL5; IGLJ14.1; IGLL; IGLL1; IGO; IGVPB; VPREB2