Product References
Airway and Lung Organoids from Human-Induced Pluripotent Stem Cells Can Be Used to Assess CFTR Conductance.
International journal of molecular sciences
Demchenko A,Kondrateva E,Tabakov V,Efremova A,Salikhova D,Bukharova T,Goldshtein D,Balyasin M,Bulatenko N,Amelina E,Lavrov A,Smirnikhina S
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Mon Mar 27 00:00:00 EDT 2023
Dynamics of CXCR4 positive circulating tumor cells in prostate cancer patients during radiotherapy.
International journal of cancer
Klusa D,Lohaus F,Franken A,Baumbach M,Cojoc M,Dowling P,Linge A,Offermann A,Löck S,Hušman D,Rivandi M,Polzer B,Freytag V,Lange T,Neubauer H,Kücken M,Perner S,Hölscher T,Dubrovska A,Krause M,Kurth I,Baumann M,Peitzsch C
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Thu Jun 15 00:00:00 EDT 2023
Parallel functional assessment of m6A sites in human endodermal differentiation with base editor screens.
Nature communications
Cheng W,Liu F,Ren Z,Chen W,Chen Y,Liu T,Ma Y,Cao N,Wang J
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Tue Jan 25 00:00:00 EST 2022
Parallel functional assessment of m6A sites in human endodermal differentiation with base editor screens.
Nature communications
Cheng W,Liu F,Ren Z,Chen W,Chen Y,Liu T,Ma Y,Cao N,Wang J
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Tue Jan 25 00:00:00 EST 2022
Rapamycin Pretreatment Rescues the Bone Marrow AML Cell Elimination Capacity of CAR-T Cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
Nian Z,Zheng X,Dou Y,Du X,Zhou L,Fu B,Sun R,Tian Z,Wei H
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
Cotargeting of miR-126-3p and miR-221-3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling.
Molecular oncology
Di Paolo D,Pontis F,Moro M,Centonze G,Bertolini G,Milione M,Mensah M,Segale M,Petraroia I,Borzi C,Suatoni P,Brignole C,Perri P,Ponzoni M,Pastorino U,Sozzi G,Fortunato O
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Mon Nov 01 00:00:00 EDT 2021
Senescent Tumor Cells Build a Cytokine Shield in Colorectal Cancer.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Choi YW,Kim YH,Oh SY,Suh KW,Kim YS,Lee GY,Yoon JE,Park SS,Lee YK,Park YJ,Kim HS,Park SH,Kim JH,Park TJ
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma.
Nature communications
Zhang S,Jiang VC,Han G,Hao D,Lian J,Liu Y,Zhang R,McIntosh J,Wang R,Dang M,Dai E,Wang Y,Santos D,Badillo M,Leeming A,Chen Z,Hartig K,Bigcal J,Zhou J,Kanagal-Shamanna R,Ok CY,Lee H,Steiner RE,Zhang J,Song X,Nair R,Ahmed S,Rodriquez A,Thirumurthi S,Jain P,Wagner-Bartak N,Hill H,Nomie K,Flowers C,Futreal A,Wang L,Wang M
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Mon May 17 00:00:00 EDT 2021
Associations between Hypertriglyceridemia and Circulating Neutrophil Subpopulation in Patients with Dyslipidemia.
International journal of inflammation
Genkel V,Dolgushin I,Baturina I,Savochkina A,Kuznetsova A,Pykhova L,Shaposhnik I
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Sun Apr 24 00:00:00 EDT 2022
Production and cryopreservation of definitive endoderm from human pluripotent stem cells under defined and scalable culture conditions.
Nature protocols
Sahabian A,Dahlmann J,Martin U,Olmer R
17-9999-42 was used in Cell Culture to show that this protocol should facilitate the flexible production of mature DE derivatives for physiologically relevant disease models, high-throughput drug screening, toxicology testing and cellular therapies.
Mon Mar 01 00:00:00 EST 2021
Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4.
Frontiers in immunology
Burkard T,Dreis C,Herrero San Juan M,Huhn M,Weigert A,Pfeilschifter JM,Radeke HH
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Wed Oct 20 00:00:00 EDT 2021
Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4.
Frontiers in immunology
Burkard T,Dreis C,Herrero San Juan M,Huhn M,Weigert A,Pfeilschifter JM,Radeke HH
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Wed Oct 20 00:00:00 EDT 2021
DNAJB6, a Key Factor in Neuronal Sensitivity to Amyloidogenesis.
Molecular cell
Thiruvalluvan A,de Mattos EP,Brunsting JF,Bakels R,Serlidaki D,Barazzuol L,Conforti P,Fatima A,Koyuncu S,Cattaneo E,Vilchez D,Bergink S,Boddeke EHWG,Copray S,Kampinga HH
17-9999 was used in Flow cytometry/Cell sorting to show that stem cells are intrinsically protected against amyloidogenesis and protein aggregates are dominantly prese in vivo.nt in neurons due to loss of DNAJB6 expression upon differentiation.
Thu Apr 16 00:00:00 EDT 2020
Circulating Progenitor Cells in Patients With Coronary Artery Disease and Renal Insufficiency.
JACC. Basic to translational science
Mehta A,Tahhan AS,Liu C,Dhindsa DS,Nayak A,Hooda A,Moazzami K,Islam SJ,Rogers SC,Almuwaqqat Z,Mokhtari A,Hesaroieh I,Ko YA,Waller EK,Quyyumi AA
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Sat Aug 01 00:00:00 EDT 2020
Defective Localization With Impaired Tumor Cytotoxicity Contributes to the Immune Escape of NK Cells in Pancreatic Cancer Patients.
Frontiers in immunology
Lim SA,Kim J,Jeon S,Shin MH,Kwon J,Kim TJ,Im K,Han Y,Kwon W,Kim SW,Yee C,Kim SJ,Jang JY,Lee KM
17-9999-42 was used in Flow Cytometry to investigate NK cell defects within pancreatic ductal adenocarcinoma.
Wed Aug 12 00:00:00 EDT 2020
Modulatory effects of trophoblast-secreted CXCL12 on the migration and invasion of human first-trimester decidual epithelial cells are mediated by CXCR4 rather than CXCR7.
Reproductive biology and endocrinology : RB&E
Zheng J,Wang H,Zhou W
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Fri Mar 02 00:00:00 EST 2018
The CXCR4 antagonist plerixafor (AMD3100) promotes proliferation of Ewing sarcoma cell lines in vitro and activates receptor tyrosine kinase signaling.
Cell communication and signaling : CCS
Berning P,Schaefer C,Clemens D,Korsching E,Dirksen U,Potratz J
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Fri May 18 00:00:00 EDT 2018
A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV.
eLife
OhAinle M,Helms L,Vermeire J,Roesch F,Humes D,Basom R,Delrow JJ,Overbaugh J,Emerman M
17-9999 was used in Flow cytometry/Cell sorting to identify interferon-induced HIV restriction factors.
Thu Dec 06 00:00:00 EST 2018
Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
PLoS pathogens
Gavegnano C,Brehm JH,Dupuy FP,Talla A,Ribeiro SP,Kulpa DA,Cameron C,Santos S,Hurwitz SJ,Marconi VC,Routy JP,Sabbagh L,Schinazi RF,Sékaly RP
17-9999 was used in Flow cytometry/Cell sorting to evaluate the ability of tofacitinib and ruxolitinib, two FDA-approved Jak inhibitors, to block seeding and maintenance of the HIV reservoir in vitro.
Fri Dec 01 00:00:00 EST 2017
Effects of pharmacological and genetic disruption of CXCR4 chemokine receptor function in B-cell acute lymphoblastic leukaemia.
British journal of haematology
Randhawa S,Cho BS,Ghosh D,Sivina M,Koehrer S,Müschen M,Peled A,Davis RE,Konopleva M,Burger JA
17-9999 was used in Flow cytometry to indicate that anti-leukaemia activity of CXCR4 antagonists is primarily due to CXCR4 inhibition, rather than agonistic activity, and corroborate that CXCR4 is an important target to overcome stroma-mediated drug resistance in B-ALL.
Mon Aug 01 00:00:00 EDT 2016
ST8SIA4-Dependent Polysialylation is Part of a Developmental Program Required for Germ Layer Formation from Human Pluripotent Stem Cells.
Stem cells (Dayton, Ohio)
Berger RP,Sun YH,Kulik M,Lee JK,Nairn AV,Moremen KW,Pierce M,Dalton S
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Fri Jul 01 00:00:00 EDT 2016
Repurposing Treprostinil for Enhancing Hematopoietic Progenitor Cell Transplantation.
Molecular pharmacology
Kazemi Z,Bergmayr C,Prchal-Murphy M,Javaheri T,Themanns M,Pham HT,Strohmaier W,Sexl V,Freissmuth M,Zebedin-Brandl E
17-9999 was used in Flow cytometry/Cell sorting to assess whether treprostinil, a prostacyclin analog, could be repurposed to improve hematopoietic stem cell transplantation.
Wed Jun 01 00:00:00 EDT 2016
In Vitro Modeling of Alcohol-Induced Liver Injury Using Human-Induced Pluripotent Stem Cells.
Methods in molecular biology (Clifton, N.J.)
Tian L,Prasad N,Jang YY
Published figure using CD184 (CXCR4) monoclonal antibody (Product # 17-9999-42) in Flow Cytometry
Thu Aug 18 00:00:00 EDT 2016
Bulk cell density and Wnt/TGFbeta signalling regulate mesendodermal patterning of human pluripotent stem cells.
Nature communications
Kempf H,Olmer R,Haase A,Franke A,Bolesani E,Schwanke K,Robles-Diaz D,Coffee M,Göhring G,Dräger G,Pötz O,Joos T,Martinez-Hackert E,Haverich A,Buettner FFR,Martin U,Zweigerdt R
17-9999 was used in Flow cytometry/Cell sorting to demonstrate a functional role of bulk cell density, and show its utility as a method to control lineage-specific differentiation.
Fri Dec 09 00:00:00 EST 2016
High-Throughput HIV-Cell Fusion Assay for Discovery of Virus Entry Inhibitors.
Assay and drug development technologies
Marin M,Du Y,Giroud C,Kim JH,Qui M,Fu H,Melikyan GB
17-9999 was used in Flow cytometry/Cell sorting to adapt and optimise an enzymatic HIV-cell fusion assay for revealing potential targets for antiviral therapy.
Wed Apr 01 00:00:00 EDT 2015
POL5551, a novel and potent CXCR4 antagonist, enhances sensitivity to chemotherapy in pediatric ALL.
Oncotarget
Sison EA,Magoon D,Li L,Annesley CE,Romagnoli B,Douglas GJ,Tuffin G,Zimmermann J,Brown P
17-9999 was used in Flow cytometry/Cell sorting to assess the potential for POL5551 to improve outcomes in children with high-risk acute lymphoblastic leukaemia.
Tue Oct 13 00:00:00 EDT 2015
Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition.
Oncotarget
Sison EA,Magoon D,Li L,Annesley CE,Rau RE,Small D,Brown P
17-9999 was used in Flow cytometry/Cell sorting to demonstrate that cells which upregulate surface CXCR4 in response to chemotherapy treatment are protected from chemotherapy-induced apoptosis when co-cultured with bone marrow stroma.
Wed Oct 15 00:00:00 EDT 2014
Combined flow cytometric analysis of surface and intracellular antigens reveals surface molecule markers of human neuropoiesis.
PloS one
Turaç G,Hindley CJ,Thomas R,Davis JA,Deleidi M,Gasser T,Karaöz E,Pruszak J
17-9999 was used in Flow cytometry/Cell sorting to develop a validated protocol enabling the co-detection and co-expression of surface molecules on neural cell populations.
Tue Feb 04 00:00:00 EST 2014
The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody.
Blood
Benson DM,Bakan CE,Mishra A,Hofmeister CC,Efebera Y,Becknell B,Baiocchi RA,Zhang J,Yu J,Smith MK,Greenfield CN,Porcu P,Devine SM,Rotem-Yehudar R,Lozanski G,Byrd JC,Caligiuri MA
17-9999 was used in Flow cytometry/Cell sorting to examine the NK cell response against MM, mediated by the PD-1/PD-L1 signalling axis and CT-011.
Thu Sep 30 00:00:00 EDT 2010