|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Nalm 1 Human cell line|
|Storage buffer||PBS with 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay-Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 4 publications below|
The TRI-COLOR® conjugate is a tandem R-phycoerythrin (PE)-Cy5® conjugate that permits simultaneous multicolor labeling and detection of multiple targets with excitation by a single excitation source-the 488 nm line of the argon-ion laser.
CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lamda light chains. It appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and malignant B cell proliferation. It is expressed in all B cell precursor leukemias.
Class 2 Device
Cytokine signatures of innate and adaptive immunity in 17DD yellow fever vaccinated children and its association with the level of neutralizing antibody.
MHCD1906 was used in flow cytometry to discuss the live attenuated yellow fever vaccines.
|Luiza-Silva M,Campi-Azevedo AC,Batista MA,Martins MA,Avelar RS,da Silveira Lemos D,Bastos Camacho LA,de Menezes Martins R,de Lourdes de Sousa Maia M,Guedes Farias RH,da Silva Freire M,Galler R,Homma A,Leite Ribeiro JG,Campos Lemos JA,Auxiliadora-Martins M,Eloi-Santos SM,Teixeira-Carvalho A,Martins-Filho OA||The Journal of infectious diseases (204:873)||2011|
Multiple co-stimulatory signals are required for triggering proliferation of T cells from human secondary lymphoid tissue.
MHCD1906 was used in flow cytometry to compare the immune responses of T cells isolated from human secondary lymphoid organs and peripheral blood.
|Agrawal SG,Marquet J,Plumas J,Rouard H,Delfau-Larue MH,Gaulard P,Boumsell L,Reyes F,Bensussan A,Farcet JP||International immunology (13:441)||2001|
CD28/CTLA-4 and CD80/CD86 costimulatory molecules are mainly involved in acceptance or rejection of human liver transplant.
MHCD1906 was used in flow cytometry to study the role of CD28/CTLA-4/B7 signaling in liver rejection.
|Minguela A,Marín L,Torío A,Muro M,García-Alonso AM,Moya-Quiles MR,Sánchez-Bueno F,Parrilla P,Alvarez-López MR||Human immunology (61:658)||2000|
Quantitative analysis of CD79b, CD5 and CD19 in mature B-cell lymphoproliferative disorders.
MHCD1906 was used in flow cytometry to investigate if expression of CD79b, CD5, and CD19 can be used to diagnose B-cell disorders.
|Cabezudo E,Carrara P,Morilla R,Matutes E||Haematologica (84:413)||1999|