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|Tested species reactivity||Human, Mouse|
|Published species reactivity||Human, Rhesus monkey|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Human thymus cells|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||2 ug/test|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:100-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects CD1a in mouse and human samples in FACS, WB and IHC (P) applications.
At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 is expressed on cortical thymocytes, Langerhans cells, and dendritic cells. It is absent on mature peripheral blood T cells but intracytoplasmic expression is detected on activated T lymphocytes. CD1 proteins have been demonstrated to restrict T-cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
An intraosseous sclerosing odontogenic tumor predominantly composed of epithelial cells: relation to (so-called) sclerosing odontogenic carcinoma and epithelial-rich central odontogenic fibroma.
MA5-12526 was used in immunohistochemistry to report on a case of an intraosseous sclerosing odontogenic tumor in a 31 year-old woman
|Tan SH,Yeo JF,Kheem Pang BN,Petersson F||Oral surgery, oral medicine, oral pathology and oral radiology (118:e119)||2014|
Role of Langerhans cells, Ki-67 protein and apoptosis in acquired cholesteatoma: prospective clinical study.
MA5-12526 was used in immunohistochemistry to study the role of Langerhans cells in the pathogenesis of acquired cholesteatoma
|Akdogan V,Yilmaz I,Canpolat T,Ozluoglu LN||The Journal of laryngology and otology (127:252)||2013|
CXCL17 and ICAM2 are associated with a potential anti-tumor immune response in early intraepithelial stages of human pancreatic carcinogenesis.
MA5-12526 was used in immunohistochemistry to study the association of CXCL17 and ICAM2 with a potential anti-tumor immune response in early stage pancreatic tumorigenesis
|Hiraoka N,Yamazaki-Itoh R,Ino Y,Mizuguchi Y,Yamada T,Hirohashi S,Kanai Y||Gastroenterology (140:310)||2011|
Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer.
MA5-12526 was used in immunohistochemistry to use biomolecular network reconstruction to investigate the immune responses in colorectal cancer patients
|Mlecnik B,Tosolini M,Charoentong P,Kirilovsky A,Bindea G,Berger A,Camus M,Gillard M,Bruneval P,Fridman WH,Pagès F,Trajanoski Z,Galon J||Gastroenterology (138:1429)||2010|
Coordination of intratumoral immune reaction and human colorectal cancer recurrence.
MA5-12526 was used in immunohistochemistry to study the correlation of intratumoral immune markers and human colorectal cancer escape
|Camus M,Tosolini M,Mlecnik B,Pagès F,Kirilovsky A,Berger A,Costes A,Bindea G,Charoentong P,Bruneval P,Trajanoski Z,Fridman WH,Galon J||Cancer research (69:2685)||2009|
Altered expression of the receptor-ligand pair CXCR5/CXCL13 in B cells during chronic HIV-1 infection.
MA5-12526 was used in immunohistochemistry to study the expression of the receptor-ligand pair CXCR5/CXCL13 in B cells during chronic HIV-1 infection
|Cagigi A,Mowafi F,Phuong Dang LV,Tenner-Racz K,Atlas A,Grutzmeier S,Racz P,Chiodi F,Nilsson A||Blood (112:4401)||2008|
|Rhesus monkey||Not Cited||
Immunogenicity of DNA vaccines encoding simian immunodeficiency virus antigen targeted to dendritic cells in rhesus macaques.
MA5-12526 was used in immunocytochemistry to study the effect on immunogenicity of targeting DNA vaccines encoding SIV antigen to dendritic cells in a non-human primate model
|Tenbusch M,Ignatius R,Nchinda G,Trumpfheller C,Salazar AM,Töpfer K,Sauermann U,Wagner R,Hannaman D,Tenner-Racz K,Racz P,Stahl-Hennig C,Uberla K||PloS one (7:null)||2012|
Tumor-derived TGFbeta-1 induces dendritic cell apoptosis in the sentinel lymph node.
MA5-12526 was used in immunocytochemistry to study the role of tumor-derived TGFbeta-1 in dendritic cell apoptosis in the sentinel lymph node
|Ito M,Minamiya Y,Kawai H,Saito S,Saito H,Nakagawa T,Imai K,Hirokawa M,Ogawa J||Journal of immunology (Baltimore, Md. : 1950) (176:5637)||2006|
a polypeptide; CD1; CD1A antigen; CD1A antigen, a polypeptide; cluster of differentiation 1 A; cortical thymocyte antigen CD1A; differentiation antigen CD1-alpha-3; epidermal dendritic cell marker CD1a; FCB6; hTa1 thymocyte antigen; R4; T-cell surface antigen T6/Leu-6; T6
CD1; CD1A; FCB6; HTA1; R4; T6