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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1/IgG2a|
|Immunogen||T lymphocytes activated by mixed lymphocyte culture and human peripheral blood T lymphocytes|
|Conjugate||FITC , PE|
|Storage buffer||PBS with 0.2% carrier protein|
|Contains||0.08% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is a monoclonal mixture of FITC-conjugated CD8 (clone 17D8, isotype IgG1) and PE-conjugated CD2 (clone T6.3, isotype IgG2a).
CD8 molecule is composed of two chains termed alpha and beta. CD8 is found on a T cell subset of normal cytotoxic / suppressor cells which make up approximately 20 to 35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer cells, 80% of thymocytes, on a subpopulation of 30% of peripheral blood null cells and 15 to 30% of bone marrow cells. CD2 is found on the majority of human T and NK cells. CD2 presents on 78+8% normal peripheral lymphocytes and 100% of thymocytes. This antibody detects CD2 antigen
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
2CD2 antigen; CD2; CD8; CD8 antigen, alpha polypeptide (p32); CD8 antigen, beta polypeptide 1 (p37); CD8a; CD8alpha; CD8b; CD8beta; Erythrocyte receptor; Leu-2; Leu2 T-lymphocyte antigen; LFA-2; LFA-3 receptor; lymphocyte-function antigen-2; MAL; OKT8 T-cell antigen; Rosette receptor; sheep red blood cell receptor; T cell co-receptor; T lymphocyte surface glycoprotein beta chain; T-cell antigen Leu2; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein CD8 beta chain; T-lymphocyte differentiation antigen T8/Leu-2; T8 T-cell antigen
CD2; CD8; CD8A; CD8B; CD8B1; LEU2; LFA-2; LY3; LYT3; MAL; p32; P37; SRBC; T11