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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant fragment encoding the external domain of the human CD2 protein|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||2 ug/test|
|Immunohistochemistry (Paraffin) (IHC (P))||1:30-1:60|
|Western Blot (WB)||1:100-1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-11373 targets CD2 in IHC (P) and FACS applications and shows reactivity with Human samples.
The MA5-11373 immunogen is recombinant fragment encoding the external domain of the human CD2 protein.
CD2 which is also known as E-rosette receptor, T11 and lymphocyte-function antigen-2 (LFA-2)) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsi are tyrosine-phosphorylated after CD2 stimulation. CD2 play a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Human Immunodeficiency Virus (HIV)-Negative and Human Herpes Virus-8 (HHV-8)-Positive Primary Effusion Lymphoma: A Case Report and Review of the Literature.
MA5-11373 was used in immunocytochemistry and immunohistochemistry to report on a case of HIV-negative/HHV-8-positive primary effusion lymphoma
|Güven Karataş S,Bayrak R,Sahin Balçık O,Yalçın KS,Atıcı E,Akyıldız U,Koşar A||Turkish journal of haematology : official journal of Turkish Society of Haematology (30:67)||2013|
Anaplastic large cell lymphoma with paraneoplastic leukocytosis: a clinicopathological analysis of five cases.
MA5-11373 was used in immunohistochemistry to report on five cases of anaplastic large cell lymphoma with paraneoplastic leukocytosis
|Chang IW,Chen HK,Ma MC,Huang WT||APMIS : acta pathologica, microbiologica, et immunologica Scandinavica (119:794)||2011|