|Flow Cytometry (Flow)||1:20|
|Immunohistochemistry (Paraffin) (IHC (P))||1:30-1:60|
|Western Blot (WB)||1:100-1:500|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant fragment encoding the external domain of the human CD2 protein|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-11373 targets CD2 in IHC (P) and FACS applications and shows reactivity with Human samples.
The MA5-11373 immunogen is recombinant fragment encoding the external domain of the human CD2 protein.
CD2 which is also known as E-rosette receptor, T11 and lymphocyte-function antigen-2 (LFA-2)) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56lck, p59fyn, CD3eta and CD3epsi are tyrosine-phosphorylated after CD2 stimulation. CD2 play a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD2; CD2 antigen; Erythrocyte receptor; LFA-2; LFA-3 receptor; lymphocyte-function antigen-2; Rosette receptor; sheep red blood cell receptor; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5
Gene Aliases: CD2; LFA-2; SRBC; T11
UniProt ID: (Human) P06729
Entrez Gene ID: (Human) 914
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.