|Tested species reactivity||Human|
|Host / Isotype||E.coli|
|Storage buffer||0.05M tris HCl, pH 7.5, with 10mM L-glutathione|
|Storage Conditions||-20°C or -80°C if preferred|
|Tested Applications||Dilution *|
|Control (Ctrl)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This product is a GST-tagged recombinant protein corresponding to human CD2, aa 25-209.
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 46kDa.
CD2, also known as E-rosette receptor, T11 and lymphocyte-function antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, lck fyn, p59 , CD3eta human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 plays a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.