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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Storage buffer||PBS with 0.5% saccharose, 0.2% gelatin|
|Contains||0.1% sodium azide|
|Storage Conditions||4°C or -80°C if preferred|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-7649 detects CD22 from human samples.
MA1-7649 has been successfully used in flow cytometry procedures.
The MA1-7649 immunogen is B-lymphocytes.
CD22 (BL-CAM) is a type 1 integral membrane glycoprotein with molecular weight of 130 to 140 kD. It is expressed in both the cytoplasm and cell membrane of B-lymphocytes. CD22 antigen appears early in B-cell lymphocyte differentiation at approximately the same stage as the CD19 antigen. Unlike other B-cell markers, CD22 membrane expression is limited to the late differentiation stages comprised between mature B cells (CD22+) and plasma cells (CD22-), and may thus prove useful in phenotyping mature leukemias. CD22 is also strongly expressed in hairy cell leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
B-lymphocyte cell adhesion molecule; BL-CAM; CD22 antigen; FLJ22814; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; SIGLEC-2; SIGLEC2; T-cell surface antigen Leu-14
CD22; SIGLEC-2; SIGLEC2