Invitrogen
Applications | Tested Dilution | Publications |
---|---|---|
Flow Cytometry (Flow) |
Neat-1:10 | - |
Immunoprecipitation (IP) |
Assay-dependent | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
DX11 |
Immunogen |
Human cytotoxic T lymphocyte clone |
Conjugate |
Biotin
|
Form |
Liquid |
Concentration |
0.1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS with 1% BSA |
Contains |
0.09% sodium azide |
Storage conditions |
4°C or -20°C if preferred |
RRID |
AB_2745127 |
This antibody recognizes human CD226, approximately a 65 kDa glycoprotein, also known as DNAM1 (DNAX accessory molecule-1). CD226 is broadly expressed on T-cells, NK cells, platelets, monocytes and a subset of B cells.
DNAM 1 is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adhesion glycoprotein; CD226; CD226 antigen; DNAM 1; DNAM-1; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; T lineage-specific activation antigen 1 antigen
Gene Aliases: CD226; DNAM-1; DNAM1; PTA1; TLiSA1
UniProt ID: (Human) Q15762
Entrez Gene ID: (Human) 10666
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