|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant external domain of CD23 protein|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:20-1:40|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 8 publications below|
MA5-14054 targets CD23 in IHC (P) applications and shows reactivity with Human samples.
The MA5-14054 immunogen is recombinant external domain of CD23 protein.
CD23 is identical to low affinity IgE receptor found on B cells. CD23 is expressed on a subpopulation of peripheral blood cells, B lymphocytes and on EBV transformed B lymphoblastoid cell lines. CD23 is also detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases on centroblastic/centrocytic lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Occurrence of nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects.
MA5-14054 was used in immunohistochemistry to study factors associated with nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome
|Lorenzi L,Tabellini G,Vermi W,Moratto D,Porta F,Notarangelo LD,Patrizi O,Sozzani S,de Saint Basile G,Latour S,Pace D,Lonardi S,Facchetti F,Badolato R,Parolini S||PloS one (8:null)||2013|
Folliculocentric B-cell-rich follicular dendritic cells sarcoma: a hitherto unreported morphological variant mimicking lymphoproliferative disorders.
MA5-14054 was used in immunohistochemistry to study three clinical cases of follicular dendritic cell sarcoma
|Lorenzi L,Lonardi S,Petrilli G,Tanda F,Bella M,Laurino L,Rossi G,Facchetti F||Human pathology (43:209)||2012|
Identification of CXCL13 as a new marker for follicular dendritic cell sarcoma.
MA5-14054 was used in immunohistochemistry to study the production CXCL13 by follicular dendritic cells and its utility as a marker of follicular dendritic cell sarcoma
|Vermi W,Lonardi S,Bosisio D,Uguccioni M,Danelon G,Pileri S,Fletcher C,Sozzani S,Zorzi F,Arrigoni G,Doglioni C,Ponzoni M,Facchetti F||The Journal of pathology (216:356)||2008|
Composite splenic marginal zone lymphoma and mantle cell lymphoma arising from 2 independent B-cell clones.
MA5-14054 was used in immunohistochemistry to investigate a rare case of composite lymphoma with mantle cell lymphoma and splenic marginal zone lymphoma
|Lefebvre C,Fabre B,Vettier C,Rabin L,Florin A,Wang J,Gressin R,Jacob MC,Callanan M,Leroux D||Human pathology (38:660)||2007|
Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity.
MA5-14054 was used in immunohistochemistry to investigate the role of Noxa expression in the pathogenesis of chronic lymphocytic leukemia
|Smit LA,Hallaert DY,Spijker R,de Goeij B,Jaspers A,Kater AP,van Oers MH,van Noesel CJ,Eldering E||Blood (109:1660)||2007|
Role of dendritic cell-derived CXCL13 in the pathogenesis of Bartonella henselae B-rich granuloma.
MA5-14054 was used in immunohistochemistry to study the role of CXCL13 in Bartonella henselae B-rich granuloma pathogenesis
|Vermi W,Facchetti F,Riboldi E,Heine H,Scutera S,Stornello S,Ravarino D,Cappello P,Giovarelli M,Badolato R,Zucca M,Gentili F,Chilosi M,Doglioni C,Ponzi AN,Sozzani S,Musso T||Blood (107:454)||2006|
Diagnosis and prognosis of B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma (B-CLL/SLL) and mantle cell lymphoma (MCL).
MA5-14054 was used in immunohistochemistry to study parameters for the diagnosis and prognosis of B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma and mantle cell lymphoma
|Asaad NY,Abd El-Wahed MM,Dawoud MM||Journal of the Egyptian National Cancer Institute (17:279)||2005|
Inflammatory pseudotumor of the spleen with EBV positivity: report of a case.
MA5-14054 was used in immunohistochemistry to report on a case of inflammatory pseudotumor of the spleen involving EBV infection
|Oz Puyan F,Bilgi S,Unlu E,Yalcin O,Altaner S,Demir M,Cakir B||European journal of haematology (72:285)||2004|