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|Tested species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG2a|
|Storage buffer||PBS, pH 7.2, with sucrose, 4mg/ml BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
CD23 is a 45kDa glycoprotein, which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
BAFF activation of the ERK5 MAP kinase pathway regulates B cell survival.
MCD2305 was used in flow cytometry to study the effect of ERK1/2 and ERK5 activation on BAFF-induced B cell survival
|Jacque E,Schweighoffer E,Tybulewicz VL,Ley SC||The Journal of experimental medicine (212:883)||2015|
C-type lectin domain family 4; CD23; CD23 antigen; CD23A; CLEC4J; FC epsilon RII; fc-epsilon-RII; FCE2; IGEBF; immunoglobulin E-binding factor; low affinity immunoglobulin epsilon Fc receptor; low-affinity IgE receptor; lymphocyte IgE receptor; member J
CD23; Fce2; Fcer2; Fcer2a; Ly-42