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|Tested species reactivity||Human, Mouse|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein encoding human CD23 48-248aa|
|Storage buffer||tissue culture supernatant|
|Contains||15mM sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:2|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Western Blot (WB)||1:10-1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-14572 targets CD23 in IHC (P), Western blot and FACS applications and shows reactivity with Human and Mouse samples.
The MA5-14572 immunogen is recombinant protein encoding human CD23 48-248aa.
CD23 is a 45kDa glycoprotein, which is present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocyctic leukaemia and some cases of centroblastic/centrocytic lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
A reference image-based method for optimization of clinical immunohistochemistry.
MA5-14572 was used in immunohistochemistry to describe a new method for immunohistochemistry optimization
|Kap M,Lam KH,Ewing-Graham P,Riegman P||Histopathology (67:193)||2015|
Inadequate T follicular cell help impairs B cell immunity during HIV infection.
MA5-14572 was used in immunohistochemistry to study the expansion of follicular helper T-cells that fail to provide adequate help to B-cells in individuals with HIV infection
|Cubas RA,Mudd JC,Savoye AL,Perreau M,van Grevenynghe J,Metcalf T,Connick E,Meditz A,Freeman GJ,Abesada-Terk G,Jacobson JM,Brooks AD,Crotty S,Estes JD,Pantaleo G,Lederman MM,Haddad EK||Nature medicine (19:494)||2013|
The matricellular protein SPARC supports follicular dendritic cell networking toward Th17 responses.
MA5-14572 was used in immunohistochemistry to investigate the role of SPARC in lymphoid tissue during immune response
|Piconese S,Costanza M,Tripodo C,Sangaletti S,Musio S,Pittoni P,Poliani PL,Burocchi A,Passafaro AL,Gorzanelli A,Vitali C,Chiodoni C,Barnaba V,Pedotti R,Colombo MP||Journal of autoimmunity (37:300)||2011|
Simultaneous activity assay of two transglutaminase isozymes, blood coagulation factor XIII and transglutaminase 2, by use of fibrinogen arrays.
MA5-14572 was used in immunohistochemistry to investigate the expression pattern of SPARC in reactive lymph nodes during immune response
|Kwon MH,Jung SH,Kim YM,Ha KS||Analytical chemistry (83:8718)||2011|
Composite biclonal marginal zone lymphoma of lung and chronic lymphocytic leukemia: pathologic, phenotypic, cytogenetic, and molecular study.
MA5-14572 was used in immunohistochemistry to investigate the coexistence of mucosa-associated lymphoid tissue lymphoma and chronic lymphocytic leukemia in a patient
|Bhagavathi S,Micale MA,Douglas-Nikitin V,Ballouz S,Neumann K,Blenc AM||International journal of surgical pathology (19:377)||2011|
Pediatric lymphomas in Brazil.
MA5-14572 was used in immunohistochemistry to study the characteristics of pediatric lymphomas in the Brazilian population
|Gualco G,Klumb CE,Barber GN,Weiss LM,Bacchi CE||Clinics (Sao Paulo, Brazil) (65:1267)||2011|
Cyclin D1 expression in B-cell lymphomas.
MA5-14572 was used in immunohistochemistry to study the expression of cyclin D1 in B-cell lymphomas
|Gladkikh A,Potashnikova D,Korneva E,Khudoleeva O,Vorobjev I||Experimental hematology (38:1047)||2010|
Burkitt lymphoma in Brazil is characterized by geographically distinct clinicopathologic features.
MA5-14572 was used in immunohistochemistry to examine the unique geographic and immunohistochemical features of Burkitt lymphoma in Brazil
|Queiroga EM,Gualco G,Weiss LM,Dittmer DP,Araujo I,Klumb CE,Harrington WJ,Bacchi CE||American journal of clinical pathology (130:946)||2008|
Sarcoma of follicular dendritic cells with features of sinus lining cells--a new subtype of reticulum cell sarcoma?
MA5-14572 was used in immunohistochemistry to characterize a potentially new subtype of reticulum cell sarcoma
|Krokowski M,Merz H,Thorns C,Bernd HW,Schade U,Le Tourneau A,Diebold J,Feller AC||Virchows Archiv : an international journal of pathology (452:565)||2008|
Histological assessment of PAXgene tissue fixation and stabilization reagents.
MA5-14572 was used in immunohistochemistry - paraffin section to examine the suitability of PAXgene tissue fixation for (immuno)histological methods
|Kap M,Smedts F,Oosterhuis W,Winther R,Christensen N,Reischauer B,Viertler C,Groelz D,Becker KF,Zatloukal K,Langer R,Slotta-Huspenina J,Bodo K,de Jong B,Oelmuller U,Riegman P||PloS one (6:null)||2011|
BLAST-2; C-type lectin domain family 4; C-type lectin domain family 4 member J; C-type lectin domain family 4, member J; CD23; CD23 antigen; CD23A; CLEC4J; Fc epsilon receptor II; FC epsilon RII; Fc fragment of IgE, low affinity II, receptor for (CD23); Fc-epsilon-RII; FCE2; IGEBF; Immunoglobulin E-binding factor; immunoglobulin epsilon-chain; Low affinity immunoglobulin epsilon Fc receptor; low-affinity IgE receptor; Lymphocyte IgE receptor; member J
BLAST-2; CD23; CD23A; CLEC4J; FCE2; FCER2; Fcer2a; IGEBF; Ly-42