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Staining of C57BL/6 splenocytes with an anti-mouse CD3-eFluor® 450 antibody and 0.06 μg of a rat IgG1,K-PE-Cy®7 isotype control (left), or 0.06 μg of rat anti-mouse CD24-PE-Cy®7 monoclonal antibody (Cat. no. A14776) (right). Cells in the lymphocyte gate were used for analysis.
|Tested species reactivity||Mouse|
|Host / Isotype||Rat / IgG2b|
|Immunogen||mouse CD24 antigen.|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
CD24 is a two-chain glycosylphosphatidylinositol (GPI)-anchored glycoprotein expressed at multiple stages of B-cell development, beginning with the bone marrow pro-B-cell compartment and continuing through mature, surface Ig positive B-cells. Plasma cell expression is very low or negative. It is also expressed on the majority of B-lineage acute lymphoblastic leukemias, B-cell CCLs and B-cell non-Hodgkin's lymphomas. CD24 may play a role in regulation of B-cell proliferation and maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD24A; cluster of differentiation 24; FLJ22950; FLJ43543; heat stable antigen; lymphocyte antigen 52; M1/69-J11D heat stable antigen; MGC75043; R13-Ag; signal transducer CD24; X62 heat stable antigen
Cd24; Cd24a; HSA; Ly-52; nectadrin