|Flow Cytometry (Flow)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Flow Cytometry (Flow)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||p55 alpha chain of the human IL-2 receptor|
|Storage buffer||PBS with 0.5% BSA|
|Contains||0.1% sodium azide|
|Storage conditions||4° C|
M10AR targets CD25 in ICC/IF, FACS, IHC, IP, and WB applications and shows reactivity with Human samples.
The M10AR immunogen is p55 alpha chain of the human IL-2 receptor.
M10AR detects CD25 which has a predicted molecular weight of approximately 28 kDa.
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD25; IL-2 receptor subunit alpha; IL-2R alpha chain; IL-2R subunit alpha; IL2 RA antibody; Il2ra antibody; Interleukin 2 receptor alpha chain antibody; interleukin 2 receptor, alpha; Interleukin-2 receptor subunit alpha; p55; TAC antigen; TAC antigen antibody
Gene Aliases: CD25; IDDM10; IL2R; IL2RA; IMD41; p55; TCGFR
UniProt ID: (Human) P01589
Entrez Gene ID: (Human) 3559
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