Product References
Glibenclamide Prevents Diabetes in NOD Mice.
PloS one
Lamprianou S,Gysemans C,Bou Saab J,Pontes H,Mathieu C,Meda P
MA517812 was used in flow cytometry to explore if the anti-diabetic sulphonylurea glibenclamide protects insulin-producing cells against conditions mimicking those expected at the onset of type 1 diabetes
Tue Jul 18 00:00:00 EDT 2017
Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression.
PloS one
Goldstein JD,Burlion A,Zaragoza B,Sendeyo K,Polansky JK,Huehn J,Piaggio E,Salomon BL,Marodon G
MA517812 was used in flow cytometry to explore the role of the JAK/STAT pathway in controlling Foxp3 in regulatory T cells
Thu Aug 25 00:00:00 EDT 2016
Alternatively Activated Macrophages Boost Induced Regulatory T and Th17 Cell Responses during Immunotherapy for Colitis.
Journal of immunology (Baltimore, Md. : 1950)
Haribhai D,Ziegelbauer J,Jia S,Upchurch K,Yan K,Schmitt EG,Salzman NH,Simpson P,Hessner MJ,Chatila TA,Williams CB
MA517812 was used in flow cytometry to compare the capacity of induced T regulatory and T helper 17 cells to develop in a T cell model of colitis
Fri Apr 15 00:00:00 EDT 2016
Schistosoma mansoni Larvae Do Not Expand or Activate Foxp3+ Regulatory T Cells during Their Migratory Phase.
Infection and immunity
Redpath SA,van der Werf N,MacDonald AS,Maizels RM,Taylor MD
MA5-17812 was used in flow cytometry to investigate the induction and role of Tregs during the early pre-patent larval stage of infection with Schistosoma mansoni.
Thu Oct 01 00:00:00 EDT 2015
Multicongenic fate mapping quantification of dynamics of thymus colonization.
The Journal of experimental medicine
Ziętara N,Łyszkiewicz M,Puchałka J,Witzlau K,Reinhardt A,Förster R,Pabst O,Prinz I,Krueger A
MA5-17812 was used in immunohistochemistry to study thymus colonization and m multicongenic fate mapping quantification of dynamics
Mon Sep 21 00:00:00 EDT 2015
ICOS controls Foxp3(+) regulatory T-cell expansion, maintenance and IL-10 production during helminth infection.
European journal of immunology
Redpath SA,van der Werf N,Cervera AM,MacDonald AS,Gray D,Maizels RM,Taylor MD
MA5-17812 was used in flow cytometry to identify factors that promote the development of Foxp3(+) T regulatory cells during helminth infections
Fri Mar 01 00:00:00 EST 2013
Developmental dynamics of post-selection thymic DN iNKT.
PloS one
Yassai M,Cooley B,Gorski J
MA5-17812 was used in flow cytometry to study the kinetics of iNKT cell precursors
Tue Jan 29 00:00:00 EST 2013
Yersinia enterocolitica promotes robust mucosal inflammatory T-cell immunity in murine neonates.
Infection and immunity
Echeverry A,Saijo S,Schesser K,Adkins B
MA5-17812 was used in flow cytometry to investigate the mucosal inflammatory T-cell immunity induced by Yersinia enterocolitica infection
Sun Aug 01 00:00:00 EDT 2010
c-Myb is required for pro-B cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Fahl SP,Crittenden RB,Allman D,Bender TP
MA5-17812 was used in flow cytometry to determine the roles of c-Myb during lymphocyte development
Sun Nov 01 00:00:00 EDT 2009
CD137 costimulation of CD8+ T cells confers resistance to suppression by virus-induced regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Robertson SJ,Messer RJ,Carmody AB,Mittler RS,Burlak C,Hasenkrug KJ
MA5-17812 was used in flow cytometry to investigate chronic retroviral infections using mice infected with the Friend virus.
Tue Apr 15 00:00:00 EDT 2008
Role for CTLA-4 but not CD25+ T cells during Schistosoma mansoni infection of mice.
Parasite immunology
Walsh CM,Smith P,Fallon PG
MA5-17812 was used in flow cytometry to study the regulation of CTLA-4+ and CD25+ T cells in schistosome infection
Fri Jun 01 00:00:00 EDT 2007
A newly established murine immature dendritic cell line can be differentiated into a mature state, but exerts tolerogenic function upon maturation in the presence of glucocorticoid.
Blood
Bros M,Jährling F,Renzing A,Wiechmann N,Dang NA,Sutter A,Ross R,Knop J,Sudowe S,Reske-Kunz AB
MA5-17812 was used in flow cytometry to study a new murine immature dendritic cell line and its differentiation into a mature state, but exerts tolerogenic function upon maturation in the presence of glucocorticoid
Tue May 01 00:00:00 EDT 2007
Endogenous CD4(+) CD25(+) regulatory T cells have a limited role in the control of Trypanosoma cruzi infection in mice.
Infection and immunity
Kotner J,Tarleton R
MA5-17812 was used in flow cytometry to determine the limited role of endogenous CD4(+) CD25(+) regulatory T cells in control of Trypanosoma cruzi infection in mice
Thu Feb 01 00:00:00 EST 2007
Dectin-1 is required for beta-glucan recognition and control of fungal infection.
Nature immunology
Taylor PR,Tsoni SV,Willment JA,Dennehy KM,Rosas M,Findon H,Haynes K,Steele C,Botto M,Gordon S,Brown GD
MA5-17812 was used in flow cytometry to report that dectin-1 deficiency renders mice susceptible to infection with Candida albicans
Mon Jan 01 00:00:00 EST 2007
Pertussis toxin reduces the number of splenic Foxp3+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Cassan C,Piaggio E,Zappulla JP,Mars LT,Couturier N,Bucciarelli F,Desbois S,Bauer J,Gonzalez-Dunia D,Liblau RS
MA5-17812 was used in flow cytometry to study a reduction of the number of splenic Foxp3+ regulatory T cells by pertussis toxin
Tue Aug 01 00:00:00 EDT 2006
Antitumor activity of the TLR-5 ligand flagellin in mouse models of cancer.
Journal of immunology (Baltimore, Md. : 1950)
Sfondrini L,Rossini A,Besusso D,Merlo A,Tagliabue E,Mènard S,Balsari A
MA5-17812 was used in flow cytometry to evaluate the antitumor effects of purified Salmonella typhimurium flagellin
Thu Jun 01 00:00:00 EDT 2006
In vitro suppression of CD8+ T cell function by Friend virus-induced regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Robertson SJ,Messer RJ,Carmody AB,Hasenkrug KJ
MA5-17812 was used to investigate the mechanism involved in the suppression of CD8+ T cells by Friend retrovirus-induced T regulatory cells
Wed Mar 15 00:00:00 EST 2006
The earliest thymic progenitors in adults are restricted to T, NK, and dendritic cell lineage and have a potential to form more diverse TCRbeta chains than fetal progenitors.
Journal of immunology (Baltimore, Md. : 1950)
Lu M,Tayu R,Ikawa T,Masuda K,Matsumoto I,Mugishima H,Kawamoto H,Katsura Y
MA5-17812 was used in flow cytometry to study T cell progenitors in the adult thymus
Tue Nov 01 00:00:00 EST 2005
Stepwise development of committed progenitors in the bone marrow that generate functional T cells in the absence of the thymus.
Journal of immunology (Baltimore, Md. : 1950)
García-Ojeda ME,Dejbakhsh-Jones S,Chatterjea-Matthes D,Mukhopadhyay A,BitMansour A,Weissman IL,Brown JM,Strober S
MA5-17812 was used in flow cytometry to conclude that bone marrow committed T cell progenitors can generate functional T cells via an extrathymic pathway
Sat Oct 01 00:00:00 EDT 2005
Accelerated dendritic-cell migration and T-cell priming in SPARC-deficient mice.
Journal of cell science
Sangaletti S,Gioiosa L,Guiducci C,Rotta G,Rescigno M,Stoppacciaro A,Chiodoni C,Colombo MP
MA5-17812 was used in flow cytometry to compare Langerhans cell and dendritic-cell migration and their impact on T-cell priming in SPARC-null and -sufficient mice
Mon Aug 15 00:00:00 EDT 2005
Altered function in CD8+ T cells following paramyxovirus infection of the respiratory tract.
Journal of virology
Gray PM,Arimilli S,Palmer EM,Parks GD,Alexander-Miller MA
MA5-17812 was used in flow cytometry to use infection of the respiratory tract with paramyxovirus simian virus 5 to study lung CD8+ T cell responses
Tue Mar 01 00:00:00 EST 2005
Helminth infection protects mice from anaphylaxis via IL-10-producing B cells.
Journal of immunology (Baltimore, Md. : 1950)
Mangan NE,Fallon RE,Smith P,van Rooijen N,McKenzie AN,Fallon PG
MA5-17812 was used in flow cytometry to test if infection with Schistosoma mansoni alters the susceptibility of mice to anaphylaxis
Mon Nov 15 00:00:00 EST 2004
CD4+ T cells prevent skin autoimmunity during chronic autologous graft-versus-host-disease.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Hequet O,Vocanson M,Saint-Mézard P,Kaiserlian D,Nicolas JF,Bérard F
MA5-17812 was used in flow cytometry to test if CD4 regulatory cells prevent autologous graft-vs.-host disease
Tue Jun 01 00:00:00 EDT 2004
IL-10 regulates early IL-12-mediated immune responses induced by the radiation-attenuated schistosome vaccine.
International immunology
Hogg KG,Kumkate S,Mountford AP
MA5-17812 was used in flow cytometry to investigate how IL-10 regulates IL-12 production in skin treated with radiation-attenuated schistosomes.
Mon Dec 01 00:00:00 EST 2003
CD8+ T cells mediate recovery and immunopathology in West Nile virus encephalitis.
Journal of virology
Wang Y,Lobigs M,Lee E,Müllbacher A
MA5-17812 was used in flow cytometry to report that CD8(+) T cells are involved in both the recovery and immunopathology of infection with West Nile virus.
Mon Dec 01 00:00:00 EST 2003
A transgenic mouse model genetically tags all activated CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950)
Maris CH,Miller JD,Altman JD,Jacob J
MA5-17812 was used in flow cytometry to track the dynamics of the antiviral CD8+ T cell responses using a transgenic mouse that marks activated T cells.
Mon Sep 01 00:00:00 EDT 2003
Extensive proliferation of T cell lineage-restricted progenitors in the thymus: an essential process for clonal expression of diverse T cell receptor beta chains.
European journal of immunology
Kawamoto H,Ohmura K,Fujimoto S,Lu M,Ikawa T,Katsura Y
MA5-17812 was used in flow cytometry to assess the proliferative potential of thymic progenitors that are T cell lineage restricted.
Sat Mar 01 00:00:00 EST 2003
Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
Otten LA,Tacchini-Cottier F,Lohoff M,Annunziato F,Cosmi L,Scarpellino L,Louis J,Steimle V,Reith W,Acha-Orbea H
MA5-17812 was used in flow cytometry to investigate the role of MHC class II transactivator in T cell differentiation.
Sat Feb 01 00:00:00 EST 2003
Tumor-infiltrating macrophages induce apoptosis in activated CD8(+) T cells by a mechanism requiring cell contact and mediated by both the cell-associated form of TNF and nitric oxide.
Journal of immunology (Baltimore, Md. : 1950)
Saio M,Radoja S,Marino M,Frey AB
MA5-17812 was used in flow cytometry to examine the ability of different tumor cells to induce apoptosis of activated CD8(+) T cells in vitro.
Thu Nov 15 00:00:00 EST 2001
An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation.
Journal of immunology (Baltimore, Md. : 1950)
Kovalev GI,Franklin DS,Coffield VM,Xiong Y,Su L
MA5-17812 was used in flow cytometry to report that the inhibitor, p18(INK4c), modulates TCR-mediated T cell proliferation.
Sat Sep 15 00:00:00 EDT 2001
CD8+ tumor-infiltrating lymphocytes are primed for Fas-mediated activation-induced cell death but are not apoptotic in situ.
Journal of immunology (Baltimore, Md. : 1950)
Radoja S,Saio M,Frey AB
MA5-17812 was used in flow cytometry to characterize murine tumor-infiltrating lymphocytes.
Tue May 15 00:00:00 EDT 2001
Lymphoid environment limits superantigen and antigen-induced T cell proliferation at high precursor frequency.
European journal of immunology
Attinger A,MacDonald HR,Acha-Orbea H
MA5-17812 was used in flow cytometry to report that the lymphoid environment limits T cell proliferation in response to high superantigen levels.
Thu Mar 01 00:00:00 EST 2001
Primed T cells are more resistant to Fas-mediated activation-induced cell death than naive T cells.
Journal of immunology (Baltimore, Md. : 1950)
Inaba M,Kurasawa K,Mamura M,Kumano K,Saito Y,Iwamoto I
MA5-17812 was used in flow cytometry to study Fas-mediated activation-induced cell death in naive and primed T cells.
Sun Aug 01 00:00:00 EDT 1999
Induction of Th2 cell differentiation in the primary immune response: dendritic cells isolated from adherent cell culture treated with IL-10 prime naive CD4+ T cells to secrete IL-4.
International immunology
Liu L,Rich BE,Inobe J,Chen W,Weiner HL
MA5-17812 was used in flow cytometry to identify the initial source of IL-4 in early immune responses.
Sat Aug 01 00:00:00 EDT 1998
Homeostasis limits the development of mature CD8+ but not CD4+ thymocytes.
Journal of immunology (Baltimore, Md. : 1950)
van Meerwijk JP,Marguerat S,MacDonald HR
MA5-17812 was used in flow cytometry to identify mechanisms that regulate the generation and maturation of thymocytes.
Sun Mar 15 00:00:00 EST 1998
Development of natural killer cells, B lymphocytes, macrophages, and mast cells from single hematopoietic progenitors in culture of murine fetal liver cells.
Blood
Aiba Y,Ogawa M
MA5-17812 was used in flow cytometry to describe a method to generate mixed NK cell colony formation from single lymphohematopoietic progenitor.
Sat Nov 15 00:00:00 EST 1997
Targets of p56(lck) activity in immature thymoblasts: stimulation of the Ras/Raf/MAPK pathway.
International immunology
Lin K,Abraham KM
MA5-17812 was used in flow cytometry to demonstrate that the Ras/Raf/MAPK pathway is constitutively activated in lck-transformed immature thymoblasts.
Sat Feb 01 00:00:00 EST 1997
Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes.
Nature
Lowenthal JW,Zubler RH,Nabholz M,MacDonald HR
MA5-17812 was used in flow cytometry to compare IL-2 receptor expression on activated B and T cells
Mon Aug 19 00:00:00 EDT 1985
Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells.
Nature
Ceredig R,Lowenthal JW,Nabholz M,MacDonald HR
MA5-17812 was used in immunohistochemistry - frozen section to use Lyt-2 and L3T4 expression to identify mouse thymocyte subpopulations and study their functions
Fri Apr 19 00:00:00 EST 1985