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NeoBiotechnologies
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
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Protein Aliases: B cell maturation antigen; B-cell maturation factor; B-cell maturation protein; CD269; Tumor necrosis factor receptor superfamily member 17; tumor necrosis factor receptor superfamily, member 17
Gene Aliases: BCM; BCMA; CD269; TNFRSF13A; TNFRSF17
UniProt ID: (Human) Q02223
Entrez Gene ID: (Human) 608
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