Product References
Reprogramming of Tumor-reactive Tumor-infiltrating Lymphocytes to Human-induced Pluripotent Stem Cells.
Cancer research communications
Islam SMR,Maeda T,Tamaoki N,Good ML,Kishton RJ,Paria BC,Yu Z,Bosch-Marce M,Bedanova NM,Liu C,Kruhlak MJ,Restifo NP,Vizcardo R
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Mon May 01 00:00:00 EDT 2023
Interaction between HLA-G and NK cell receptor KIR2DL4 orchestrates HER2-positive breast cancer resistance to trastuzumab.
Signal transduction and targeted therapy
Zheng G,Guo Z,Li W,Xi W,Zuo B,Zhang R,Wen W,Yang AG,Jia L
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
Interaction between HLA-G and NK cell receptor KIR2DL4 orchestrates HER2-positive breast cancer resistance to trastuzumab.
Signal transduction and targeted therapy
Zheng G,Guo Z,Li W,Xi W,Zuo B,Zhang R,Wen W,Yang AG,Jia L
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Wed Jun 23 00:00:00 EDT 2021
Construction of Novel lncRNA-miRNA-mRNA Network Associated With Recurrence and Identification of Immune-Related Potential Regulatory Axis in Hepatocellular Carcinoma.
Frontiers in oncology
Zhan T,Gao X,Wang G,Li F,Shen J,Lu C,Xu L,Li Y,Zhang J
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Tue Aug 03 00:00:00 EDT 2021
Imaging Changes and Immune-Checkpoint Expression on T Cells in Bronchoalveolar Lavage Fluid from Patients with Pulmonary Sarcoidosis.
Biomedicines
Kotetsu Y,Yanagihara T,Suzuki K,Ando H,Eto D,Hata K,Arimura-Omori M,Yamamoto Y,Harada E,Hamada N
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Thu Sep 16 00:00:00 EDT 2021
Increased Incidence of Venous Thromboembolism with Cancer Immunotherapy.
Med (New York, N.Y.)
Roopkumar J,Swaidani S,Kim AS,Thapa B,Gervaso L,Hobbs BP,Wei W,Alban TJ,Funchain P,Kundu S,Sangwan N,Rayman P,Pavicic PG,Diaz-Montero CM,Barnard J,McCrae KR,Khorana AA
11-9969-42 was used in Flow Cytometry to investigate if venous thromboembolism is an underappreciated and important immune-related adverse event associated with cancer immunotherapy.
Fri Apr 09 00:00:00 EDT 2021
Bispecific T-Cell Engaging Antibodies Against MUC16 Demonstrate Efficacy Against Ovarian Cancer in Monotherapy and in Combination With PD-1 and VEGF Inhibition.
Frontiers in immunology
Yeku OO,Rao TD,Laster I,Kononenko A,Purdon TJ,Wang P,Cui Z,Liu H,Brentjens RJ,Spriggs D
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Thu Oct 21 00:00:00 EDT 2021
PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.
The Journal of cell biology
Xu X,Hou B,Fulzele A,Masubuchi T,Zhao Y,Wu Z,Hu Y,Jiang Y,Ma Y,Wang H,Bennett EJ,Fu G,Hui E
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Mon Jun 01 00:00:00 EDT 2020
Immunogenic neoantigens derived from gene fusions stimulate T cell responses.
Nature medicine
Yang W,Lee KW,Srivastava RM,Kuo F,Krishna C,Chowell D,Makarov V,Hoen D,Dalin MG,Wexler L,Ghossein R,Katabi N,Nadeem Z,Cohen MA,Tian SK,Robine N,Arora K,Geiger H,Agius P,Bouvier N,Huberman K,Vanness K,Havel JJ,Sims JS,Samstein RM,Mandal R,Tepe J,Ganly I,Ho AL,Riaz N,Wong RJ,Shukla N,Chan TA,Morris LGT
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Wed May 01 00:00:00 EDT 2019
According to Hepatitis C Virus (HCV) Infection Stage, Interleukin-7 Plus 4-1BB Triggering Alone or Combined with PD-1 Blockade Increases TRAF1low HCV-Specific CD8+ Cell Reactivity.
Journal of virology
Moreno-Cubero E,Subirá D,Sanz-de-Villalobos E,Parra-Cid T,Madejón A,Miquel J,Olveira A,González-Praetorius A,García-Samaniego J,Larrubia JR
11-9969 was used in Flow cytometry/Cell sorting to support novel ways of restoring the specific CD8+ T cell response, shedding light on the importance of TRAF1 signaling as a promising target for future immunotherapy during HCV infection.
Mon Jan 15 00:00:00 EST 2018
Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells.
Cell reports
Zhao Y,Harrison DL,Song Y,Ji J,Huang J,Hui E
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Tue Jul 10 00:00:00 EDT 2018
Chronic Critical Illness from Sepsis Is Associated with an Enhanced TCR Response.
Journal of immunology (Baltimore, Md. : 1950)
Borken F,Markwart R,Requardt RP,Schubert K,Spacek M,Verner M,Rückriem S,Scherag A,Oehmichen F,Brunkhorst FM,Rubio I
Thu Jun 15 00:00:00 EDT 2017
Increased levels of CCR7(lo)PD-1(hi) CXCR5+ CD4+ T cells, and associated factors Bcl-6, CXCR5, IL-21 and IL-6 contribute to repeated implantation failure.
Experimental and therapeutic medicine
Gong Q,Zhu Y,Pang N,Ai H,Gong X,La X,Ding J
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Fri Dec 01 00:00:00 EST 2017
CXCL13-producing TFH cells link immune suppression and adaptive memory in human breast cancer.
JCI insight
Gu-Trantien C,Migliori E,Buisseret L,de Wind A,Brohée S,Garaud S,Noël G,Dang Chi VL,Lodewyckx JN,Naveaux C,Duvillier H,Goriely S,Larsimont D,Willard-Gallo K
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Fri Jun 02 00:00:00 EDT 2017
Structure-guided development of a high-affinity human Programmed Cell Death-1: Implications for tumor immunotherapy.
EBioMedicine
Lázár-Molnár E,Scandiuzzi L,Basu I,Quinn T,Sylvestre E,Palmieri E,Ramagopal UA,Nathenson SG,Guha C,Almo SC
11-9969 was used in Flow cytometry/Cell sorting to highlight the value of structural considerations in the design of a PD-1 Ig fusion protein with immune modulatory properties.
Wed Mar 01 00:00:00 EST 2017
Functional characterization of T-cells from palatine tonsils in patients with chronic tonsillitis.
PloS one
Geißler K,Markwart R,Requardt RP,Weigel C,Schubert K,Scherag A,Rubio I,Guntinas-Lichius O
11-9969 was used in Flow cytometry/Cell sorting to analyse and characterise the response of tonsillar T-cells from chronic tonsillitis to antigenic stimulation.
Mon Oct 16 00:00:00 EDT 2017
Immunodominant Dengue Virus-Specific CD8+ T Cell Responses Are Associated with a Memory PD-1+ Phenotype.
Journal of virology
de Alwis R,Bangs DJ,Angelo MA,Cerpas C,Fernando A,Sidney J,Peters B,Gresh L,Balmaseda A,de Silva AD,Harris E,Sette A,Weiskopf D
11-9969 was used in Flow cytometry/Cell sorting to define DENV-specific CD8(+)T cell responses in general and those of HLA alleles associated with dominant responses.
Sun May 01 00:00:00 EDT 2016
Tumor-infiltrating Tim-3+ T cells proliferate avidly except when PD-1 is co-expressed: Evidence for intracellular cross talk.
Oncoimmunology
Li J,Shayan G,Avery L,Jie HB,Gildener-Leapman N,Schmitt N,Lu BF,Kane LP,Ferris RL
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Tue Jan 12 00:00:00 EST 2021
IL12-mediated sensitizing of T-cell receptor-dependent and -independent tumor cell killing.
Oncoimmunology
Braun M,Ress ML,Yoo YE,Scholz CJ,Eyrich M,Schlegel PG,Wölfl M
11-9969 was used in Flow cytometry/Cell sorting to investigate how IL12, and other inflammatory cytokines, shape effector functions of human T-cells.
Fri Jul 01 00:00:00 EDT 2016
Monoclonal antibodies specific to human Δ42PD1: A novel immunoregulator potentially involved in HIV-1 and tumor pathogenesis.
mAbs
Cheng L,Tang X,Liu L,Peng J,Nishiura K,Cheung AK,Guo J,Wu X,Tang HY,An M,Zhou J,Cheung KW,Wang H,Guan X,Wu Z,Chen Z
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Tue Mar 22 00:00:00 EDT 2016
PD-1(+) CD8(+) T cells are exhausted in tumours and functional in draining lymph nodes of colorectal cancer patients.
British journal of cancer
Wu X,Zhang H,Xing Q,Cui J,Li J,Li Y,Tan Y,Wang S
11-9969 was used in Flow cytometry/Cell sorting to evaluate the role of PD-1-PD-L1 pathway in CD8(+) T-cell functions in tumour-draining lymph nodes (TDLNs) and tumours of CRC patients.
Tue Sep 23 00:00:00 EDT 2014
IL-17 and IFN-γ expression in lymphocytes from patients with active tuberculosis correlates with the severity of the disease.
Journal of leukocyte biology
Jurado JO,Pasquinelli V,Alvarez IB,Peña D,Rovetta AI,Tateosian NL,Romeo HE,Musella RM,Palmero D,Chuluyán HE,García VE
11-9969 was used in Flow cytometry/Cell sorting to investigate the induction and regulation of IFN-γ and IL-17 during active human Mycobacterium tuberculosis infection.
Fri Jun 01 00:00:00 EDT 2012
Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients.
Critical care (London, England)
Zhang Y,Li J,Lou J,Zhou Y,Bo L,Zhu J,Zhu K,Wan X,Cai Z,Deng X
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Wed Dec 07 00:00:00 EST 2011
The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody.
Blood
Benson DM,Bakan CE,Mishra A,Hofmeister CC,Efebera Y,Becknell B,Baiocchi RA,Zhang J,Yu J,Smith MK,Greenfield CN,Porcu P,Devine SM,Rotem-Yehudar R,Lozanski G,Byrd JC,Caligiuri MA
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Flow Cytometry
Thu Sep 30 00:00:00 EDT 2010
PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients.
Leukemia
Kozako T,Yoshimitsu M,Fujiwara H,Masamoto I,Horai S,White Y,Akimoto M,Suzuki S,Matsushita K,Uozumi K,Tei C,Arima N
11-9969 was used in Flow cytometry/Cell sorting to determine whether the PD-1/PD-L1 pathway could be involved in the establishment of persistent HTLV-1 infections.
Sun Feb 01 00:00:00 EST 2009
Impaired CD4 and CD8 effector function and decreased memory T cell populations in ICOS-deficient patients.
Journal of immunology (Baltimore, Md. : 1950)
Takahashi N,Matsumoto K,Saito H,Nanki T,Miyasaka N,Kobata T,Azuma M,Lee SK,Mizutani S,Morio T
11-9969 was used in Flow cytometry/Cell sorting to investigate the effect of ICOS deficiency on T cell immune responses, showing that it leads to impaired CD4 and CD8 effector function and decreased memory T cell populations.
Fri May 01 00:00:00 EDT 2009
Regulatory T cell (Treg) subsets return in patients with refractory lupus following stem cell transplantation, and TGF-beta-producing CD8+ Treg cells are associated with immunological remission of lupus.
Journal of immunology (Baltimore, Md. : 1950)
Zhang L,Bertucci AM,Ramsey-Goldman R,Burt RK,Datta SK
11-9969 was used in Flow cytometry/Cell sorting to show that after hemopoietic stem cell posttransplant patients certain Treg populations return to levels seen in healthy patient.
Sun Nov 15 00:00:00 EST 2009
Spontaneous recovery in acute human hepatitis C virus infection: functional T-cell thresholds and relative importance of CD4 help.
Journal of virology
Smyk-Pearson S,Tester IA,Klarquist J,Palmer BE,Pawlotsky JM,Golden-Mason L,Rosen HR
11-9969 was used in Flow cytometry/Cell sorting to examine total HCV-specific CD4(+) and CD8(+) T-cell responses in acute HCV infection and identify functional T-cell thresholds that predict recovery.
Fri Feb 01 00:00:00 EST 2008
Programmed death-1 expression is associated with the disease status in hepatitis B virus infection.
World journal of gastroenterology
Ye P,Weng ZH,Zhang SL,Zhang JA,Zhao L,Dong JH,Jie SH,Pang R,Wei RH
11-9969 was used in Flow cytometry/Cell sorting to confirm a negative correlation between the level of PD-1 and the intensity of virus specific CD8+ T cell response.
Mon Jul 28 00:00:00 EDT 2008
FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy.
BMC cancer
Ghebeh H,Barhoush E,Tulbah A,Elkum N,Al-Tweigeri T,Dermime S
Published figure using CD279 (PD-1) monoclonal antibody (Product # 11-9969-42) in Immunohistochemistry
Sat Feb 23 00:00:00 EST 2008
PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors.
Blood
Zhang JY,Zhang Z,Wang X,Fu JL,Yao J,Jiao Y,Chen L,Zhang H,Wei J,Jin L,Shi M,Gao GF,Wu H,Wang FS
Fri Jun 01 00:00:00 EDT 2007
T regulatory cell levels decrease in people infected with Schistosoma mansoni on effective treatment.
The American journal of tropical medicine and hygiene
Watanabe K,Mwinzi PN,Black CL,Muok EM,Karanja DM,Secor WE,Colley DG
11-9969 was used in Flow cytometry/Cell sorting to investigate the role of Tregs in Schistosoma mansoni infection, showing that Treg levels decrease in people on effective treatment.
Mon Oct 01 00:00:00 EDT 2007