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|Tested species reactivity||Human, Primate|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human CD28 transfected into murine T cell hybridoma.|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||15mM sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||5 µl for 10^6 cells in 100 µl|
|Immunocytochemistry (ICC)||Assay dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-20792 detects CD28 in human and non-human primate samples.
MA1-20792 has been successfully used in IF, FACS, immunocytochemistry, and immunohistochemistry (frozen) procedures.
The MA1-20792 immunogen is human CD28 transfected into mouse T cell hybridoma.
Human CD28 antigen is a 44 kDa disulfide linked homodimeric T cell specific surface glycoprotein. It is a cell adhesion molecule of the immunoglobulin superfamily which is constitutively expressed on most peripheral blood T lymphocytes (approximately 95% of CD4+ cells and 50% of CD8+ cells). Mature thymocytes exhibit higher levels of CD28 than the immature cells. Activation of T cells results in enhanced CD28 expression. T cell activation requires two combined signals provided by antigen presenting cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD28 antigen; MGC138290; Tp44