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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:40-1:80|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 8 publications below|
MA5-13219 targets CD30 in IHC (P) applications and shows reactivity with Human samples.
The MA5-13219 immunogen is co cells.
CD30, a single chain glycoprotein, is synthesized as a 90kDa precursor which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. The CD30/Ki-1 antigen is expressed by mononuclear Hodgkin and multinucleated Reed-Sternberg cells in Hodgkin's disease, by the tumor cells of a majority of anaplastic large cell lymphomas, and by a varying proportion of activated T and B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD30(+) extranodal natural killer/T-cell lymphoma mimicking phlegmonous myositis: A case report.
MA5-13219 was used in immunohistochemistry to report on a case of CD30-positive extranodal natural killer/T-cell lymphoma
|Yang YJ,Li YX,Liu YB,Yang M,Liu K||Oncology letters (7:1419)||2014|
Clinicopathology, immunophenotype, T cell receptor gene rearrangement, Epstein-Barr virus status and p53 gene mutation of cutaneous extranodal NK/T-cell lymphoma, nasal-type.
MA5-13219 was used in immunohistochemistry to study the potential association of a range of factors with nasal type cutaneous extranodal natural killer/T-cell lymphoma
|Wang TT,Xu C,Liu SL,Kan B,Ran YP,Liu WP,Li GD,Wang L||Chinese medical journal (126:1281)||2013|
Composite lymphoma in the anterior mediastinum: a case report and review of the literature.
MA5-13219 was used in immunohistochemistry to present a case report of an unusual composite lymphoma in the mediastinum
|Yu G,Kong L,Qu G,Zhang Q,Wang W,Jiang L||Diagnostic pathology (6:null)||2011|
Copy number alterations and expression profiles of candidate genes in a pulmonary inflammatory myofibroblastic tumor.
MA5-13219 was used in immunohistochemistry to study the pathogenic mechanisms of pulmonary inflammatory myofibroblastic tumor
|Jung SH,Yim SH,Hu HJ,Jung CK,Lee SH,Kim DH,Chung YJ||Lung cancer (Amsterdam, Netherlands) (70:152)||2010|
Diagnostic and differential diagnostic criteria of lymphoid neoplasms in bone marrow trephine biopsies: a study of 87 cases.
MA5-13219 was used in immunohistochemistry to investigate the diagnosis of lymphoid neoplasmas through bone marrow trephine biopsies
|Horváth E,Mezei T,Pávai Z,Turcu M,Demian S,Tóth E,Chira L,Jung I||Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie (50:399)||2009|
Nuclear and cytoplasmic AID in extrafollicular and germinal center B cells.
MA5-13219 was used in immunohistochemistry to investigate Intracellular distribution of activation-induced cytidine deaminase in extrafollicular and germinal center B cells
|Cattoretti G,Büttner M,Shaknovich R,Kremmer E,Alobeid B,Niedobitek G||Blood (107:3967)||2006|
PRDM1/Blimp-1 is expressed in human B-lymphocytes committed to the plasma cell lineage.
MA5-13219 was used in immunohistochemistry to study the role of PRDM1/Blimp-1 in human B-lymphocyte differentiation
|Cattoretti G,Angelin-Duclos C,Shaknovich R,Zhou H,Wang D,Alobeid B||The Journal of pathology (206:76)||2005|
Inflammatory pseudotumor of the spleen with EBV positivity: report of a case.
MA5-13219 was used in immunohistochemistry to report on a case of inflammatory pseudotumor of the spleen involving EBV infection
|Oz Puyan F,Bilgi S,Unlu E,Yalcin O,Altaner S,Demir M,Cakir B||European journal of haematology (72:285)||2004|
CD30 antigen; CD30L receptor; cytokine receptor CD30; Ki-1 antigen; lymphocyte activation antigen CD30; tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily, member 8
CD30; D1S166E; Ki-1; TNFRSF8