Neuropilin 1 is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor and semaphorin family members. Neuropilin 1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration and invasion.
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Protein Aliases: A5 protein; CD304; Neuropilin-1; Neuropilin-1 precursor (A5 protein); transmembrane receptor; Vascular endothelial cell growth factor 165 receptor
Gene Aliases: BDCA4; C530029I03; CD304; NP-1; NP1; NPN-1; Npn1; NRP; NRP1; VEGF165R
Molecular Function: apolipoprotein cell adhesion molecule enzyme modulator extracellular matrix protein hydrolase membrane-bound signaling molecule metalloprotease oxidase oxidoreductase protease receptor serine protease signaling molecule transfer/carrier protein transporter