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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 151-303 of human NCR1 |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
2.37 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2805812 |
Immunogen sequence: SMFLLLKEGR SSHVQRGYGK VQAEFPLGPV TTAHRGTYRC FGSYNNHAWS FPSEPVKLLV TGDIENTSLA PEDPTFPDTW GTYLLTTETG LQKDHALWDH TAQNLLRMGL AFLVLVALVW FLVEDWLSRK RTRERASRAS TWEGRRRLNT QTL; Positive Samples: A-549, Mouse spleen, Mouse thymus, Rat spleen, Rat lung; Cellular Location: Cell membrane, Single-pass type I membrane protein
NKp46 (CD335, NCR1, ) is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. NKp46 consists of two Ig-like domains assembled to leukocyte immunoglobulin-like (LIR) and killer inhibitory receptors (KIR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1-Mar; Activating receptor 1; CD335; hNKp46; Ly-94; Lymphocyte antigen 94; Lymphocyte antigen 94 homolog; lymphocyte antigen 94 homolog (activating NK-receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); mAR-1; MAR1 (mouse activating receptor 1); mNKp46; Natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; natural killer cell receptor; NK cell-activating receptor; NK receptor KILR-1; NK-p46; NK-p46); NKACTR; rAR-1; rat-activating receptor 1
Gene Aliases: Ar1; CD335; KILR-1; Kilr1; LY94; NCR1; NK-p46; NKP46
UniProt ID: (Human) O76036, (Rat) Q9Z0H5, (Mouse) Q8C567
Entrez Gene ID: (Human) 9437, (Rat) 117547, (Mouse) 17086
Molecular Function:
immunoglobulin receptor superfamily
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