|Tested species reactivity||Mouse|
|Host / Isotype||Rat / IgG1|
|Immunogen||Fusion protein composed of the E. coli maltose binding protein andmouse bcrp protein (residues 221-394).|
|Storage buffer||tissue culture supernatant with 0.7% BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (FACS)||Assay dependent|
|Immunohistochemistry (Frozen) (IHC (F))||1:20|
|Western Blot (WB)||1:20-1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-35032 does not react with human BCRP.
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, the human protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. This protein likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.