|Flow Cytometry (FACS)||Assay dependent|
|Immunohistochemistry (Frozen) (IHC (F))||1:20|
|Western Blot (WB)||1:20-1:50|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rat / IgG1|
|Immunogen||Fusion protein composed of the E. coli maltose binding protein andmouse bcrp protein (residues 221-394).|
|Storage buffer||tissue culture supernatant with 0.7% BSA|
|Contains||0.1% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA1-35032 does not react with human BCRP.
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, the human protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. This protein likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-binding cassette sub-family G member 2; breast cancer resistance protein 1 homolog; mitoxantrone resistance protein 1; urate exporter
Gene Aliases: ABC15; ABCP; AI428558; BCRP; Bcrp1; MXR; MXR1
UniProt ID: (Mouse) Q9Z1T0
Entrez Gene ID: (Mouse) 26357
Molecular Function: Transporter
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