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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Hematopoietic precursor cells.|
|Storage buffer||PBS with 0.2% gelatin, 0.5% saccharose|
|Contains||0.1% sodium azide|
|Storage Conditions||4°C or -80°C if preferred|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-7652 detects CD34 from human samples.
MA1-7652 has been successfully used in flow cytometry procedures.
The MA1-7652 immunogen is Hematopoietic precursor cells.
CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. CD34 is thought to have a role in presenting carbohydrate ligands to selectins. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD34 antigen; hematopoietic progenitor cell antigen CD34; Mucosialin; RP11-328D5.2